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Permanent Orthopedics Job in Clarksville Tennessee with Community Health Systems, Inc
Gateway Medical Center, in Clarksville, TN, is seeking a BE/BC Orthopaedic Surgeon. Join existing single specialty group or hospital will assist in setting up solo practice. Employed or Income Guarantee
Permanent Orthopedics Job in Martin Tennessee with Community Health Systems, Inc
Martin, TN - Great Opportunity in NW Tennessee Volunteer Medical Center in Martin, TN is seeking a BE/BC Orthopedic Surgeon. Martin is home to University of Tennessee at Martin and there is an opportunity
Permanent Orthopedics Job in Edinburg Texas with Universal Health Services, Inc.
Excellent opportunity for thriving practice in Texas! South Texas Health System in Edinburg and McAllen, Texas is seeking to assist an Orthopedic Surgeon with starting up a new practice in Edinburg.
All Orthopedic Foot and Ankle Jobs
Permanent Orthopedic Foot and Ankle Job in Atlanta Georgia with Perimeter Outpatient Surgical Associates
Our North Atlanta Practice is looking to expand. We are seeking a fellowship trained orthopaedic physician (any specialty) to join our group and utilize our on site Ambulatory Surgical Center. Our
Permanent Orthopedic Foot and Ankle Job in Call for More Information Massachusetts with Medical Search International
Busy Medical Center with all sub specialties of Orthopedics is seeking a BC/BE Orthopedic Surgeon with Foot and Ankle training. Metropolitan area! Fellows are welcomed!! Great compensation including
Permanent Orthopedic Foot and Ankle Job in Call for Information Kansas with Inhouse Physician Recruiters Network
The In-House Physician Recruiter Network, composed of over 500 hospital recruiters, represents over 10,000 hospitals and clinics. Our Network's special feature is to showcase outstanding physicians (who
Journal of Orthopaedic Trauma - Current Table Of Contents
Complications of Acetabular Fracture Surgery in Morbidly Obese Patients.
Page: 589DOI: 10.1097/BOT.0b013e318188d6c3Authors: Porter, Scott E MD; Russell, George V MD; Dews, Robert C MD; Qin, Zhen MS; Woodall, James Jr MD; Graves, Matthew L MD
Platelet-Rich Concentrate Supports Human Mesenchymal Stem Cell Proliferation, Bone Morphogenetic Protein-2 Messenger RNA Expression, Alkaline Phosphatase Activity, and Bone Formation In Vitro: A Mode of Action to Enhance Bone Repair.
Page: 595DOI: 10.1097/BOT.0b013e318188dbb7Authors: Parsons, Philippa PhD *; Butcher, Andrew BSc *; Hesselden, Katy BSc *; Ellis, Keith MSc *; Maughan, Jonathan BSc *; Milner, Richard PhD *; Scott, Marcus PhD +; Alley, Carie MSc +; Watson, J Tracy MD ++; Horner, Alan PhD *
Does a Volar Locking Plate Provide Equivalent Stability as a Dorsal Nonlocking Plate in a Dorsally Comminuted Distal Radius Fracture?: A Biomechanical Study.
Page: 605DOI: 10.1097/BOT.0b013e318186006fAuthors: Kandemir, Utku MD *; Matityahu, Amir MD *; Desai, Rohan BS *; Puttlitz, Christian PhD +
Archives of Orthopaedic and Trauma Surgery
Differences in patellofemoral contact stresses between mobile-bearing and fixed-bearing total knee arthroplasties: a dynamic in vitro measurement
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Introduction Anterior knee pain is one of the most common problems after total knee arthroplasty (TKA). Mobile-bearing designs should improve patella tracking with a reduced rate of patella tilt as well as reduced patellofemoral contact stresses and improve knee flexion. The aim of this dynamic in vitro investigation was to evaluate the changes of patellofemoral contact stresses after TKA using fixed and mobile-bearing designs. Materials and methods Seven knee specimens were mounted into a knee simulator imitating an isokinetic extension of the knee. The patellofemoral contact was measured before and after tricompartimental TKA with fixed and mobile-bearing designs using pressure-sensitive films. Contact stresses were measured from 120° knee flexion to full extension with a simulated force of the quadriceps muscle up to 1,200 N. Additionally all measurements were performed with simulated co-contraction of the hamstrings muscles. Results Fixed-bearing TKA increases patellofemoral contact stresses compared to physiologic conditions. After patella resurfacing, contact stresses increase even more. By changing the prosthesis design to mobile bearing, maximum contact stress was measured to be punctual higher than in fixed-bearing implants. In the interval between 0°–30° and 70°–105° of flexion, obviously lower pressures were evaluated for the mobile-bearing design. With cocontraction of the hamstrings, a lower contact stress of the mobile-bearing design was evident for the complete measurement of the knee extension. Conclusion An increase of patellofemoral contact stresses after patellar resurfacing in TKA could be demonstrated. This outcome implicates a higher risk of patellofemoral complications. The mobile-bearing design showed evidently lower patellofemoral contact stresses than the fixed-bearing design. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0757-9Authors Adrian Skwara, University Hospital Marburg Department of Orthopaedics and Rheumatology Baldingerstrasse 35043 Marburg GermanyCarsten O. Tibesku, sporthopaedicum Straubing Straubing GermanySven Ostermeier, Medical School Hannover (MHH) Department of Orthopaedics Hannover GermanyChristina Stukenborg-Colsman, Medical School Hannover (MHH) Department of Orthopaedics Hannover GermanySusanne Fuchs-Winkelmann, University Hospital Marburg Department of Orthopaedics and Rheumatology Baldingerstrasse 35043 Marburg Germany Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
The usefulness of dual energy X-ray and laser absorptiometry of the calcaneus versus dual energy X-ray absorptiometry of hip and spine in diagnosing manifest osteoporosis
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Introduction Osteoporosis is a major health problem. Dual energy X-ray absorptiometry (DXA) of the hip and spine is the worldwide standard in diagnosing osteoporosis. Measurement of bone mineral density (BMD) with dual energy X-ray and laser absorptiometry of the calcaneus (Calscan) might be a good alternative. Advantages of the Calscan are that it is quick, widely available and manageable. In this study we compared BMD expressed in T-scores measured by DXA and Calscan. The aim of this study was to define threshold T-scores on the Calscan that could exclude or predict osteoporosis correctly in comparison with DXA. Materials and methods Patients ≥50 years attending our emergency department with a fracture were offered osteoporosis screening at our fracture and osteoporosis outpatient clinic (FO-Clinic) and enrolled in this study. BMD was measured at the hip and spine using DXA and at the calcaneus using Calscan. A T-score measured by DXA ≤−2 standard deviations (SD) below the reference population was defined as manifest osteoporosis and was the treatment threshold. Results During a 10-month study period, 182 patients were screened with both devices. The mean DXA-T-score was −1.63 SD (range −4.9 to 2.1) and Calscan T-score −1.91 SD (range −5.3 to 1.4). There was a significant correlation between both devices (r = 0.47, P < 0.01). Using an upper threshold for the Calscan T-score of −1.3 SD, 47 patients could be classified as non-osteoporotic with 89.3% sensitivity (95% CI 80.0–95.3%). Using a lower threshold for the Calscan T-score of −2.9 SD, 34 patients could be classified by the Calscan as osteoporotic with 90.7% specificity (95% CI 83.5–95.4). The remaining 101 patients could only be correctly classified by DXA-T-scores. Conclusion Although DXA is the established modality worldwide in measuring BMD it is restricted to specialized centres. Peripheral bone densitometers like the Calscan are widely available. When BMD measurements with DXA were compared to Calscan measurements it was possible to correctly classify 81 of 182 patients based on the Calscan T-score. Of these 81 patients 34 could be classified as manifest osteoporotic and 47 as non-osteoporotic. Therefore the Calscan seems to be a promising technique which might be used as a screening device at a FO-Clinic, especially when DXA is not easily available. Content Type Journal ArticleCategory Osteoporotic Fracture ManagementDOI 10.1007/s00402-008-0755-yAuthors Gijs de Klerk, Twenteborg Ziekenhuis Department of Surgery Zilvermeeuw 1 7609 PP Almelo The NetherlandsD. van der Velde, Twenteborg Ziekenhuis Department of Surgery Zilvermeeuw 1 7609 PP Almelo The NetherlandsJ. van der Palen, Medisch Spectrum Twente Department of Epidemiology Enschede The NetherlandsL. van Bergeijk, Twenteborg Ziekenhuis Department of Internal Medicine Almelo The NetherlandsJ. H. Hegeman, Twenteborg Ziekenhuis Department of Surgery Zilvermeeuw 1 7609 PP Almelo The Netherlands Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
The recovery of 5-HT transporter and 5-HT immunoreactivity in injured rat spinal cord
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Study design Experimental spinal cord injury. Objective To determine the role of serotonin (5-HT) and 5-HT transporter in recovery from spinal cord injury. Method We examined 5-HT and 5-HT transporter of spinal cord immunohistologically and assessed locomotor recovery after extradural compression at the thoracic (T8) spinal cord in 21 rats. Eighteen rats had laminectomy and spinal cord injury, while the remaining three rats received laminectomy only. All rats were evaluated every other day for 4 weeks, using a 0–14 point scale open field test. Results Extradural compression markedly reduced mean hindlimbs scores from 14 to 1.5 ± 2.0 (mean ± standard error of mean). The rats recovered apparently normal walking by 4 weeks. The animals were perfused with fixative 1–3 days, 1, 2 and 4 weeks (three rats in each) after a spinal cord injury. The 5-HT transporter immunohistological study revealed a marked reduction of 5-HT transporter-containing terminals by 1 day after injury. By 4 weeks after injury, 5-HT transporter immunoreactive terminals returned to the control level. The 5-HT immunohistological study revealed a reduction of 5-HT-containing terminals by 1 week after injury. By 4 weeks after injury, 5-HT immunoreactive fibers and terminals returned to the control level. Conclusion We estimated the recovery of 5-HT transporter and 5-HT neural elements in lumbosacral ventral horn by ranking 5-HT transporter and 5-HT staining intensity and counting 5-HT and 5-HT transporter terminals. The return of 5-HT transporter and 5-HT immunoreactivity of the lumbosacral ventral horn correlated with locomotor recovery, while 5-HT transporter showed closer relationship with locomotor recovery than 5-HT. The presence of 5-HT transporter indicates that the 5-HT fibers certainly function. This study shows that return of the function of 5-HT fibers predict the time course and extent of locomotory recovery after thoracic spinal cord injury. Content Type Journal ArticleCategory Basic ScienceDOI 10.1007/s00402-008-0754-zAuthors Yasuo Saruhashi, Shiga University of Medical Science Department of Orthopedic Surgery Setatsukinowacho Otsu Shiga 520-2192 JapanYoshitaka Matsusue, Shiga University of Medical Science Department of Orthopedic Surgery Setatsukinowacho Otsu Shiga 520-2192 JapanMineko Fujimiya, Shiga University of Medical Science Department of Anatomy Otsu Japan Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Deep vein thrombosis after total hip arthroplasty in Korean patients and D-dimer as a screening tool
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Introduction This prospective study was designed to confirm risk factors and to assess the incidence of deep vein thrombosis after total hip and surface replacement arthroplasty in Korean patients not receiving anticoagulation prophylaxis and to determine efficacy of plasma D-dimer levels as a screening test. Materials and methods From May 2003 to August 2004, 221 consecutive patients undergoing unilateral total hip arthroplasty and hip resurfacing were evaluated. All patients underwent ultrasonography preoperatively and venography and/or ultrasonography on postoperative day 7. Plasma D-dimer levels were estimated by latex immuno-assay preoperatively and on days 3 and 7 postoperatively. Results Of the 221 patients in our cohort, 23 developed deep vein thrombosis (10.4%). Age (r = 0.245, P < 0.001) and gender (r = 0.155, P = 0.021) significantly correlated with deep vein thrombosis. Rise in incidence paralleled increase in age (X2 = 32.860, P < 0.001). D-dimer levels on postoperative days 3 (γ = 0.364, P < 0.001) and 7 (γ = 0.470, P < 0.001) were significantly correlated to the development of DVT. Conclusion While incidence of deep vein thrombosis in Korean population after THA was lower than that in the West; it increased with age, and in female gender. Significant correlation was found between D-dimer levels and the development of deep vein thrombosis. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0751-2Authors Myung-Chul Yoo, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South KoreaYoon-Je Cho, Kyung Hee University Medical Center Department of Orthopaedic Surgery Seoul 130-702 South KoreaElie Ghanem, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South KoreaAlankar Ramteke, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South KoreaKang-Il Kim, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South Korea Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Reconstruction of the proximal humerus with a composite of extracorporeally irradiated bone and endoprosthesis following excision of high grade primary bone sarcomas
Mon, 29 Sep 2008 20:19:04 -0000
Abstract Introduction Functional reconstruction of the shoulder joint following excision of a malignant proximal humeral tumour is a difficult proposition. Method Eleven patients with primary osteosarcoma or Ewing’s sarcoma underwent reconstruction with a composite of extra-corporeally irradiated autograft with the addition of a long stemmed hemiarthroplasty. At a mean follow-up of 5.8 years two patients had died from disseminated disease and one patient had undergone amputation for local recurrence. The eight patients with a surviving limb were examined clinically and radiographically. Result The mean Toronto Extremity Salvage Score was 74 and Musculo-Skeletal Tumour Society score 66. Rotation was well preserved but abduction (mean 32°) and flexion (40°) were poor. There was a high rate of secondary surgery, with five out of eleven patients requiring re-operation for complications of reconstruction surgery. Radiographic estimate of graft remaining at follow up was 71%. There were no infections, revisions or radiographic failures. Conclusion Whilst the reconstructions were durable in the medium term, the functional outcome was no better than with other reported reconstructive methods. The composite technique was especially useful in subtotal humeral resections, allowing preservation of the elbow joint even with very distal osteotomy. Bone stock is restored, which may be useful for future revision surgery in this young group of patients. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0752-1Authors Matthew Moran, Royal Prince Alfred Hospital Department of Orthopaedic Surgery Missenden Road, Camperdown Sydney NSW 2055 AustraliaPaul D. Stalley, Royal Prince Alfred Hospital Department of Orthopaedic Surgery Missenden Road, Camperdown Sydney NSW 2055 Australia Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Periarticular muscle stimulation controls anterior tibial laxity after experimental ACL section: an experimental study
Mon, 29 Sep 2008 20:19:03 -0000
Abstract Background and purpose Besides current strategies to treat potentially disabling anterior cruciate ligament (ACL) injury, a new and innovative approach was designed based on electrical stimulation of the muscle to prevent unwanted displacement of the tibia relative to the femur. Our aim was to measure muscular strain and anterior tibial translation (ATT) in a controlled study using an animal model of ACL-deficient knee undergoing muscular electric stimulation. Methods Seventeen cat knees under tibial anterior traction of 24.5 N were studied before and after ACL transection. Muscular fiber length variation was obtained by ultrasonomicrometry and ATT by video recordings at the beginning, during, and at the end of the movement. Square pulses of 0.2 ms with 5 V were applied in trains of 500, 100, and 20 ms simultaneously to both the quadriceps and hamstrings before and immediately after traction. Results Electric stimulation of ACL-deficient knees normalized muscular strain to values of control knees. An increased resistance to muscular lengthening was observed in stimulated knees. Stimulation before traction maintained similar ATT than control knees during the subsequent traction. Discussion Electric muscular stimulation in the ACL-deficient knee provoked periarticular muscle contraction, controlling ATT when time-adjusted stimulus (before traction) was used. This suggested that artificially inducing the muscular response could help to control anterior knee laxity after ACL injury. Content Type Journal ArticleCategory Arthroscopy and Sports MedicineDOI 10.1007/s00402-008-0763-yAuthors Nuria Bonsfills, Hospital Universitario La Paz Unidad de Ortopedia Pediátrica, Hospital Infantil Paseo de la Castellana, 261 28046 Madrid SpainAngel Nuñez, Universidad Autónoma de Madrid Departamento de Anatomía, Histología y Neurociencia, Facultad de Medicina Madrid SpainEnrique Gomez-Barrena, Universidad Autónoma de Madrid Departamento de Cirugía, Facultad de Medicina Madrid Spain Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
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Permanent Orthopedics Job in Clarksville Tennessee with Community Health Systems, Inc
Gateway Medical Center, in Clarksville, TN, is seeking a BE/BC Orthopaedic Surgeon. Join existing single specialty group or hospital will assist in setting up solo practice. Employed or Income Guarantee
Permanent Orthopedics Job in Martin Tennessee with Community Health Systems, Inc
Martin, TN - Great Opportunity in NW Tennessee Volunteer Medical Center in Martin, TN is seeking a BE/BC Orthopedic Surgeon. Martin is home to University of Tennessee at Martin and there is an opportunity
Permanent Orthopedics Job in Edinburg Texas with Universal Health Services, Inc.
Excellent opportunity for thriving practice in Texas! South Texas Health System in Edinburg and McAllen, Texas is seeking to assist an Orthopedic Surgeon with starting up a new practice in Edinburg.
All Orthopedic Foot and Ankle Jobs
Permanent Orthopedic Foot and Ankle Job in Atlanta Georgia with Perimeter Outpatient Surgical Associates
Our North Atlanta Practice is looking to expand. We are seeking a fellowship trained orthopaedic physician (any specialty) to join our group and utilize our on site Ambulatory Surgical Center. Our
Permanent Orthopedic Foot and Ankle Job in Call for More Information Massachusetts with Medical Search International
Busy Medical Center with all sub specialties of Orthopedics is seeking a BC/BE Orthopedic Surgeon with Foot and Ankle training. Metropolitan area! Fellows are welcomed!! Great compensation including
Permanent Orthopedic Foot and Ankle Job in Call for Information Kansas with Inhouse Physician Recruiters Network
The In-House Physician Recruiter Network, composed of over 500 hospital recruiters, represents over 10,000 hospitals and clinics. Our Network's special feature is to showcase outstanding physicians (who
Journal of Orthopaedic Trauma - Current Table Of Contents
Complications of Acetabular Fracture Surgery in Morbidly Obese Patients.
Page: 589DOI: 10.1097/BOT.0b013e318188d6c3Authors: Porter, Scott E MD; Russell, George V MD; Dews, Robert C MD; Qin, Zhen MS; Woodall, James Jr MD; Graves, Matthew L MD
Platelet-Rich Concentrate Supports Human Mesenchymal Stem Cell Proliferation, Bone Morphogenetic Protein-2 Messenger RNA Expression, Alkaline Phosphatase Activity, and Bone Formation In Vitro: A Mode of Action to Enhance Bone Repair.
Page: 595DOI: 10.1097/BOT.0b013e318188dbb7Authors: Parsons, Philippa PhD *; Butcher, Andrew BSc *; Hesselden, Katy BSc *; Ellis, Keith MSc *; Maughan, Jonathan BSc *; Milner, Richard PhD *; Scott, Marcus PhD +; Alley, Carie MSc +; Watson, J Tracy MD ++; Horner, Alan PhD *
Does a Volar Locking Plate Provide Equivalent Stability as a Dorsal Nonlocking Plate in a Dorsally Comminuted Distal Radius Fracture?: A Biomechanical Study.
Page: 605DOI: 10.1097/BOT.0b013e318186006fAuthors: Kandemir, Utku MD *; Matityahu, Amir MD *; Desai, Rohan BS *; Puttlitz, Christian PhD +
Archives of Orthopaedic and Trauma Surgery
Differences in patellofemoral contact stresses between mobile-bearing and fixed-bearing total knee arthroplasties: a dynamic in vitro measurement
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Introduction Anterior knee pain is one of the most common problems after total knee arthroplasty (TKA). Mobile-bearing designs should improve patella tracking with a reduced rate of patella tilt as well as reduced patellofemoral contact stresses and improve knee flexion. The aim of this dynamic in vitro investigation was to evaluate the changes of patellofemoral contact stresses after TKA using fixed and mobile-bearing designs. Materials and methods Seven knee specimens were mounted into a knee simulator imitating an isokinetic extension of the knee. The patellofemoral contact was measured before and after tricompartimental TKA with fixed and mobile-bearing designs using pressure-sensitive films. Contact stresses were measured from 120° knee flexion to full extension with a simulated force of the quadriceps muscle up to 1,200 N. Additionally all measurements were performed with simulated co-contraction of the hamstrings muscles. Results Fixed-bearing TKA increases patellofemoral contact stresses compared to physiologic conditions. After patella resurfacing, contact stresses increase even more. By changing the prosthesis design to mobile bearing, maximum contact stress was measured to be punctual higher than in fixed-bearing implants. In the interval between 0°–30° and 70°–105° of flexion, obviously lower pressures were evaluated for the mobile-bearing design. With cocontraction of the hamstrings, a lower contact stress of the mobile-bearing design was evident for the complete measurement of the knee extension. Conclusion An increase of patellofemoral contact stresses after patellar resurfacing in TKA could be demonstrated. This outcome implicates a higher risk of patellofemoral complications. The mobile-bearing design showed evidently lower patellofemoral contact stresses than the fixed-bearing design. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0757-9Authors Adrian Skwara, University Hospital Marburg Department of Orthopaedics and Rheumatology Baldingerstrasse 35043 Marburg GermanyCarsten O. Tibesku, sporthopaedicum Straubing Straubing GermanySven Ostermeier, Medical School Hannover (MHH) Department of Orthopaedics Hannover GermanyChristina Stukenborg-Colsman, Medical School Hannover (MHH) Department of Orthopaedics Hannover GermanySusanne Fuchs-Winkelmann, University Hospital Marburg Department of Orthopaedics and Rheumatology Baldingerstrasse 35043 Marburg Germany Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
The usefulness of dual energy X-ray and laser absorptiometry of the calcaneus versus dual energy X-ray absorptiometry of hip and spine in diagnosing manifest osteoporosis
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Introduction Osteoporosis is a major health problem. Dual energy X-ray absorptiometry (DXA) of the hip and spine is the worldwide standard in diagnosing osteoporosis. Measurement of bone mineral density (BMD) with dual energy X-ray and laser absorptiometry of the calcaneus (Calscan) might be a good alternative. Advantages of the Calscan are that it is quick, widely available and manageable. In this study we compared BMD expressed in T-scores measured by DXA and Calscan. The aim of this study was to define threshold T-scores on the Calscan that could exclude or predict osteoporosis correctly in comparison with DXA. Materials and methods Patients ≥50 years attending our emergency department with a fracture were offered osteoporosis screening at our fracture and osteoporosis outpatient clinic (FO-Clinic) and enrolled in this study. BMD was measured at the hip and spine using DXA and at the calcaneus using Calscan. A T-score measured by DXA ≤−2 standard deviations (SD) below the reference population was defined as manifest osteoporosis and was the treatment threshold. Results During a 10-month study period, 182 patients were screened with both devices. The mean DXA-T-score was −1.63 SD (range −4.9 to 2.1) and Calscan T-score −1.91 SD (range −5.3 to 1.4). There was a significant correlation between both devices (r = 0.47, P < 0.01). Using an upper threshold for the Calscan T-score of −1.3 SD, 47 patients could be classified as non-osteoporotic with 89.3% sensitivity (95% CI 80.0–95.3%). Using a lower threshold for the Calscan T-score of −2.9 SD, 34 patients could be classified by the Calscan as osteoporotic with 90.7% specificity (95% CI 83.5–95.4). The remaining 101 patients could only be correctly classified by DXA-T-scores. Conclusion Although DXA is the established modality worldwide in measuring BMD it is restricted to specialized centres. Peripheral bone densitometers like the Calscan are widely available. When BMD measurements with DXA were compared to Calscan measurements it was possible to correctly classify 81 of 182 patients based on the Calscan T-score. Of these 81 patients 34 could be classified as manifest osteoporotic and 47 as non-osteoporotic. Therefore the Calscan seems to be a promising technique which might be used as a screening device at a FO-Clinic, especially when DXA is not easily available. Content Type Journal ArticleCategory Osteoporotic Fracture ManagementDOI 10.1007/s00402-008-0755-yAuthors Gijs de Klerk, Twenteborg Ziekenhuis Department of Surgery Zilvermeeuw 1 7609 PP Almelo The NetherlandsD. van der Velde, Twenteborg Ziekenhuis Department of Surgery Zilvermeeuw 1 7609 PP Almelo The NetherlandsJ. van der Palen, Medisch Spectrum Twente Department of Epidemiology Enschede The NetherlandsL. van Bergeijk, Twenteborg Ziekenhuis Department of Internal Medicine Almelo The NetherlandsJ. H. Hegeman, Twenteborg Ziekenhuis Department of Surgery Zilvermeeuw 1 7609 PP Almelo The Netherlands Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
The recovery of 5-HT transporter and 5-HT immunoreactivity in injured rat spinal cord
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Study design Experimental spinal cord injury. Objective To determine the role of serotonin (5-HT) and 5-HT transporter in recovery from spinal cord injury. Method We examined 5-HT and 5-HT transporter of spinal cord immunohistologically and assessed locomotor recovery after extradural compression at the thoracic (T8) spinal cord in 21 rats. Eighteen rats had laminectomy and spinal cord injury, while the remaining three rats received laminectomy only. All rats were evaluated every other day for 4 weeks, using a 0–14 point scale open field test. Results Extradural compression markedly reduced mean hindlimbs scores from 14 to 1.5 ± 2.0 (mean ± standard error of mean). The rats recovered apparently normal walking by 4 weeks. The animals were perfused with fixative 1–3 days, 1, 2 and 4 weeks (three rats in each) after a spinal cord injury. The 5-HT transporter immunohistological study revealed a marked reduction of 5-HT transporter-containing terminals by 1 day after injury. By 4 weeks after injury, 5-HT transporter immunoreactive terminals returned to the control level. The 5-HT immunohistological study revealed a reduction of 5-HT-containing terminals by 1 week after injury. By 4 weeks after injury, 5-HT immunoreactive fibers and terminals returned to the control level. Conclusion We estimated the recovery of 5-HT transporter and 5-HT neural elements in lumbosacral ventral horn by ranking 5-HT transporter and 5-HT staining intensity and counting 5-HT and 5-HT transporter terminals. The return of 5-HT transporter and 5-HT immunoreactivity of the lumbosacral ventral horn correlated with locomotor recovery, while 5-HT transporter showed closer relationship with locomotor recovery than 5-HT. The presence of 5-HT transporter indicates that the 5-HT fibers certainly function. This study shows that return of the function of 5-HT fibers predict the time course and extent of locomotory recovery after thoracic spinal cord injury. Content Type Journal ArticleCategory Basic ScienceDOI 10.1007/s00402-008-0754-zAuthors Yasuo Saruhashi, Shiga University of Medical Science Department of Orthopedic Surgery Setatsukinowacho Otsu Shiga 520-2192 JapanYoshitaka Matsusue, Shiga University of Medical Science Department of Orthopedic Surgery Setatsukinowacho Otsu Shiga 520-2192 JapanMineko Fujimiya, Shiga University of Medical Science Department of Anatomy Otsu Japan Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Deep vein thrombosis after total hip arthroplasty in Korean patients and D-dimer as a screening tool
Tue, 30 Sep 2008 09:03:59 -0000
Abstract Introduction This prospective study was designed to confirm risk factors and to assess the incidence of deep vein thrombosis after total hip and surface replacement arthroplasty in Korean patients not receiving anticoagulation prophylaxis and to determine efficacy of plasma D-dimer levels as a screening test. Materials and methods From May 2003 to August 2004, 221 consecutive patients undergoing unilateral total hip arthroplasty and hip resurfacing were evaluated. All patients underwent ultrasonography preoperatively and venography and/or ultrasonography on postoperative day 7. Plasma D-dimer levels were estimated by latex immuno-assay preoperatively and on days 3 and 7 postoperatively. Results Of the 221 patients in our cohort, 23 developed deep vein thrombosis (10.4%). Age (r = 0.245, P < 0.001) and gender (r = 0.155, P = 0.021) significantly correlated with deep vein thrombosis. Rise in incidence paralleled increase in age (X2 = 32.860, P < 0.001). D-dimer levels on postoperative days 3 (γ = 0.364, P < 0.001) and 7 (γ = 0.470, P < 0.001) were significantly correlated to the development of DVT. Conclusion While incidence of deep vein thrombosis in Korean population after THA was lower than that in the West; it increased with age, and in female gender. Significant correlation was found between D-dimer levels and the development of deep vein thrombosis. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0751-2Authors Myung-Chul Yoo, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South KoreaYoon-Je Cho, Kyung Hee University Medical Center Department of Orthopaedic Surgery Seoul 130-702 South KoreaElie Ghanem, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South KoreaAlankar Ramteke, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South KoreaKang-Il Kim, Kyung Hee University East-West Neo Medical Center Department of Orthopaedic Surgery, Center for Joint Diseases 149 Sangil-dong Gangdong-gu Seoul 134-727 South Korea Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Reconstruction of the proximal humerus with a composite of extracorporeally irradiated bone and endoprosthesis following excision of high grade primary bone sarcomas
Mon, 29 Sep 2008 20:19:04 -0000
Abstract Introduction Functional reconstruction of the shoulder joint following excision of a malignant proximal humeral tumour is a difficult proposition. Method Eleven patients with primary osteosarcoma or Ewing’s sarcoma underwent reconstruction with a composite of extra-corporeally irradiated autograft with the addition of a long stemmed hemiarthroplasty. At a mean follow-up of 5.8 years two patients had died from disseminated disease and one patient had undergone amputation for local recurrence. The eight patients with a surviving limb were examined clinically and radiographically. Result The mean Toronto Extremity Salvage Score was 74 and Musculo-Skeletal Tumour Society score 66. Rotation was well preserved but abduction (mean 32°) and flexion (40°) were poor. There was a high rate of secondary surgery, with five out of eleven patients requiring re-operation for complications of reconstruction surgery. Radiographic estimate of graft remaining at follow up was 71%. There were no infections, revisions or radiographic failures. Conclusion Whilst the reconstructions were durable in the medium term, the functional outcome was no better than with other reported reconstructive methods. The composite technique was especially useful in subtotal humeral resections, allowing preservation of the elbow joint even with very distal osteotomy. Bone stock is restored, which may be useful for future revision surgery in this young group of patients. Content Type Journal ArticleCategory Orthopaedic SurgeryDOI 10.1007/s00402-008-0752-1Authors Matthew Moran, Royal Prince Alfred Hospital Department of Orthopaedic Surgery Missenden Road, Camperdown Sydney NSW 2055 AustraliaPaul D. Stalley, Royal Prince Alfred Hospital Department of Orthopaedic Surgery Missenden Road, Camperdown Sydney NSW 2055 Australia Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051
Periarticular muscle stimulation controls anterior tibial laxity after experimental ACL section: an experimental study
Mon, 29 Sep 2008 20:19:03 -0000
Abstract Background and purpose Besides current strategies to treat potentially disabling anterior cruciate ligament (ACL) injury, a new and innovative approach was designed based on electrical stimulation of the muscle to prevent unwanted displacement of the tibia relative to the femur. Our aim was to measure muscular strain and anterior tibial translation (ATT) in a controlled study using an animal model of ACL-deficient knee undergoing muscular electric stimulation. Methods Seventeen cat knees under tibial anterior traction of 24.5 N were studied before and after ACL transection. Muscular fiber length variation was obtained by ultrasonomicrometry and ATT by video recordings at the beginning, during, and at the end of the movement. Square pulses of 0.2 ms with 5 V were applied in trains of 500, 100, and 20 ms simultaneously to both the quadriceps and hamstrings before and immediately after traction. Results Electric stimulation of ACL-deficient knees normalized muscular strain to values of control knees. An increased resistance to muscular lengthening was observed in stimulated knees. Stimulation before traction maintained similar ATT than control knees during the subsequent traction. Discussion Electric muscular stimulation in the ACL-deficient knee provoked periarticular muscle contraction, controlling ATT when time-adjusted stimulus (before traction) was used. This suggested that artificially inducing the muscular response could help to control anterior knee laxity after ACL injury. Content Type Journal ArticleCategory Arthroscopy and Sports MedicineDOI 10.1007/s00402-008-0763-yAuthors Nuria Bonsfills, Hospital Universitario La Paz Unidad de Ortopedia Pediátrica, Hospital Infantil Paseo de la Castellana, 261 28046 Madrid SpainAngel Nuñez, Universidad Autónoma de Madrid Departamento de Anatomía, Histología y Neurociencia, Facultad de Medicina Madrid SpainEnrique Gomez-Barrena, Universidad Autónoma de Madrid Departamento de Cirugía, Facultad de Medicina Madrid Spain Journal Archives of Orthopaedic and Trauma SurgeryOnline ISSN 1434-3916Print ISSN 0936-8051

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