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Wiley: All New Psychology Titles
Brain-Based Therapy with Children and Adolescents: Evidence-Based Treatment for Everyday Practice
John B. Arden, PhD, Lloyd Linford Mon, 17 Nov 2008 05:00:00 -0000
Designed for mental health professionals treating children and adolescents, Brain-Based Therapy with Children and Adolescents: Evidence-Based Treatment for Everyday Practice is a simple but powerful primer for understanding and successfully implementing the most critical elements of neuroscience into an evidence-based mental health practice. Written for counselors, social workers, psychologists, and graduate students, this new treatment approach focuses Read More...
History of Cognitive Neuroscience
M. R. Bennett, P. M. S. Hacker Mon, 17 Nov 2008 05:00:00 -0000
In this companion work to the highly acclaimed Philosophical Foundations of Neuroscience, the distinguished neurophysiologist M. R. Bennett and eminent philosopher P. M. S. Hacker return to the relationship between brain function and our psychological attributes. While their earlier work identified the troubling conceptual issues in contemporary neuroscience, History of Cognitive Neuroscience documents the history of the study of perception and sensation Read More...
Youth, Violence, and Social Disintegration, Number 119
Wilhelm Heitmeyer (Editor), Sandra Hupping (Editor) Mon, 17 Nov 2008 05:00:00 -0000
Read More...
All Psychiatry Jobs
Locum Tenens Psychiatry Job in Government: Great job for a Psychiatrist in Walla Walla, OR. Any state license will work. Washington with CompHealth Inc
Job 0834122-0005 Any active, unrestrictive license Outpatient; Residential Treatment and Substance Abuse Rehab Programs Board Certified or Board Eligible Monday - Friday 8a-4:30p, no call NPI & BLS
Locum Tenens Psychiatry Job in Maryland Client looking for an adult psychiatrist to provide locum tenens in an inpatient setting. Maryland with CompHealth Inc
Job 0118338-0058 Inpatient adult psychiatry; see patient with general psychiatric needs as well as severe mentally ill. General census is 13.5 in a 17 bed unit. Adult psychiatrist - (Locum tenens work)
Locum Tenens Psychiatry Job in WANT SOME GREAT CHEESE? Wisconsin with CompHealth Inc
Job 1466712-0019 VISIT WISCONSIN -- THE "CHEESE" STATE MONDAY - FRIDAY 8:00-5:00 GERI INPATIENT UNIT VERY LOW CASE LOAD CALL NEEDED We offer competitive pay that may include incentives and bonuses We
All Psychiatry Adult Jobs
Permanent Psychiatry Adult Job in Oklahoma City Oklahoma with OUHSC University of Oklahoma Health Services
GENERAL PSYCHIATRIST POSITION The Department of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center, is recruiting a psychiatrist with interest in a clinician/educator track.
Permanent Psychiatry Adult Job in Plattsburgh New York with CVPH Medical Center
ADIRONDACK MOUNTAINS - LAKE CHAMPLAIN REGION CVPH Medical Center (www.cvph.org) seeks staff adult psychiatrist to do inpatient work. Hospital employed position with call of 1:4. Enjoy working with
Permanent Psychiatry Adult Job in Erie Pennsylvania with Saint Vincent Health Center
Seeking Full-time BC/BE Adult Psychiatrist to join our team of 4 adult Psychiatrists and 2 child Psychiatrists. Ideally, would like someone with an interest in Geriatric Psychiatry for our new Geriatric
Advances in Psychiatric Treatment current issue
[Articles] Psychoanalytic and psychodynamic therapies for depression: the evidence base
Taylor, D. Fri, 31 Oct 2008 00:00:00 -0000
This article argues that the current approach to guideline development for the treatment of depression is not supported by the evidence: clearly depression is not a disease for which treatment efficacy is best determined by short-term randomised controlled trials. As a result, important findings have been marginalised. Different principles of evidence-gathering are described. When a wider range of the available evidence is critically considered the case for dynamic approaches to the treatment of depression can be seen to be stronger than is often thought. Broadly, the benefits of short-term psychodynamic therapies are equivalent in size to the effects of antidepressants and cognitive–behavioural therapy (CBT). The benefits of CBT may occur more quickly, but those of short-term psychodynamic therapies may continue to increase after treatment. There may be a ceiling on the effects of short-term treatments of whatever type. Longer-term psychodynamic treatments may improve associated social, work and personal dysfunctions as well as reductions in depressive symptoms.
[Articles] Gulf War syndrome - has it gone away?
Tarn, M., Greenberg, N., Wessely, S. Fri, 31 Oct 2008 00:00:00 -0000
‘Gulf War syndrome’ was a phrase coined after the 1991 Gulf War. This article looks at the variety of hypotheses that have been put forward about the origins of the concept and the studies attempting to characterise the health manifestations of Gulf service and the lasting effects on veterans. It also serves to bring readers up to date with research on the present deployment in Iraq. Finally, consideration is given to how Gulf War syndrome compares with the rich historical literature of post-conflict medical syndromes and how sociological factors may interact with symptom attribution in veterans.
[Articles] Cannabis use by people with severe mental illness - is it important?
Atakan, Z. Fri, 31 Oct 2008 00:00:00 -0000
Cannabis use is more common among people with severe mental illness than in the general population. It has detrimental effects on the course of the illness, physical health and social life of users, as well as being a financial burden on health services. It is important to understand why some people with severe mental illness continue to use cannabis, despite experiencing its effects on their condition. This article reviews research on the scale of cannabis use by such patients, the effects on the course of their illness, possible reasons to explain why they use it, and how they can be assessed in clinical settings, as well as providing some assessment tools to measure various characteristics related to cannabis use.
Am J Psychiatry current issue
[In This Issue] In this Issue
Mon, 03 Nov 2008 00:00:00 -0000
[Editorials] New Findings on Antipsychotic Use in Children and Adolescents With Schizophrenia Spectrum Disorders
Ross, R. G. Mon, 03 Nov 2008 00:00:00 -0000
[Editorials] Depression, Bereavement, and "Understandable" Intense Sadness: Should the DSM-IV Approach Be Revised?
Maj, M. Mon, 03 Nov 2008 00:00:00 -0000
Archives of General Psychiatry current issue
ABOUT THIS JOURNAL: About This Journal
Mon, 03 Nov 2008 00:00:00 -0000
THIS MONTH IN ARCHIVES OF GENERAL PSYCHIATRY: This Month in Archives of General Psychiatry
Mon, 03 Nov 2008 00:00:00 -0000
ART AND IMAGES IN PSYCHIATRY: The Mothers (VI From Seven Woodcuts to War)
Harris, J. C. Mon, 03 Nov 2008 00:00:00 -0000
Acad Psychiatry current issue
[EDITORIALS] Wise Advice (from an Unlikely Source) for the Profession of Academic Psychiatry
Roberts, L. W. Wed, 22 Oct 2008 00:00:00 -0000
[EDITORIALS] Innovation and Inspiration in Child and Adolescent Psychiatric Education
Beresin, E. Wed, 22 Oct 2008 00:00:00 -0000
[RESEARCH ARTICLES] Increasing Interest in Child and Adolescent Psychiatry in the Third-Year Clerkship: Results from a Post-Clerkship Survey
Malloy, E., Hollar, D., Lindsey, B. A. Wed, 22 Oct 2008 00:00:00 -0000
OBJECTIVE: The authors aimed to determine whether a structured clinical experience in child and adolescent psychiatry (CAP) during the third-year psychiatry clerkship would impact interest in pursuing careers in psychiatry and CAP. METHODS: The authors constructed and administered a postrotation survey, the Child and Adolescent Psychiatry Experiences Questionnaire (CAPE-Q), to evaluate clinical experiences and career interest in psychiatry and CAP both before and after a clerkship in psychiatry. The value of specific aspects of the clerkship to students’ career decisions was also assessed. The students completed the surveys at the end of their psychiatry clerkship in the 2005–2006 academic year and in their first rotation of 2006–2007. RESULTS: Of the 98 respondents, the majority reported no change in interest in general psychiatry or in CAP after the clerkship. However, exposure to inpatient CAP correlated with increased interest in the field and in its influence on pursuing a CAP career. Interest in CAP positively correlated with agreement that the CAP clinical experience influenced their career decision. The influence of the CAP clinical experience on career decision was associated with interest in both psychiatry and CAP, as well as with change in CAP interest after the clerkship. CONCLUSION: These preliminary results suggest that the CAPE-Q may be useful for assessing students’ clerkship experiences and the impact of these experiences on their decision to pursue a career in child psychiatry. Here, inpatient CAP experience led to increased interest in the field. The CAPE-Q could be used to identify students for whom electives and mentoring opportunities could be arranged. It could also be used in assessment of clerkship experiences.
PubMed: 0924-9338
CSF monoamine metabolites and neuropeptides in depressed patients before and after electroconvulsive therapy.
Nikisch G, Mathé AA Related Articles CSF monoamine metabolites and neuropeptides in depressed patients before and after electroconvulsive therapy. Eur Psychiatry. 2008 Aug;23(5):356-9 Authors: Nikisch G, Mathé AA Antidepressant drugs affect monoamines and neuropeptides in human cerebrospinal fluid (CSF) and in rodent brain. The purpose of this study was to investigate if also electroconvulsive therapy (ECT) affects these compounds in a similar manner in the CSF of depressed patients. Homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and corticotropin-releasing hormone (CRH)-like immunoreactivity (-LI) and neuropeptide Y (NPY)-LI were determined in CSF in six drug resistant patients with major depression. Lumbar puncture was performed at baseline and after completion of eight ECTs. ECT was associated with an increase in NPY-LI (p=0.009) and a decrease in CRH-LI (p<or=0.001). HVA (p=0.003) and 5-HIAA (p=0.002) were significantly increased after the ECT. Findings of NPY increase and CRH decrease were similar to those following chronic treatment with citalopram, indicating that these changes might constitute one of the common underpinnings of antidepressant treatment modalities. PMID: 18455913 [PubMed - indexed for MEDLINE]
Association between age at onset and clinical features of schizophrenia: the Northern Finland 1966 birth cohort study.
Luoma S, Hakko H, Ollinen T, Järvelin MR, Lindeman S Related Articles Association between age at onset and clinical features of schizophrenia: the Northern Finland 1966 birth cohort study. Eur Psychiatry. 2008 Aug;23(5):331-5 Authors: Luoma S, Hakko H, Ollinen T, Järvelin MR, Lindeman S PURPOSE: To study the association between age at onset and the clinical picture of schizophrenia in an unselected young birth cohort. SUBJECTS AND METHODS: The study sample consists of 98 (64 males and 34 females) individuals with DSM-III-R schizophrenia collected from the Northern Finland 1966 birth cohort. Firstly, subjects were divided into very early- and young-onset subgroups by using the median age at onset (22 years in males and 20 in females), as a cut-off point. Secondly, we used age at onset as a continuous variable. Clinical features of schizophrenia were assessed using the Operational Criteria Checklist for Psychotic Illnesses (OCCPI). RESULTS: Inappropriate affect, positive thought disorder and deterioration from premorbid level of function associate with very early-onset schizophrenia, while slowed activity and dysphoria relate to young-onset. These symptoms correlate significantly with the age at onset. DISCUSSION: Differences in the clinical picture associating to the age at onset of schizophrenia are seen early. CONCLUSION: These findings indicate that certain symptoms of schizophrenia are dependent on the age at onset, and schizophrenia occurring initially in early life has some typical features. Using the age at onset as a continuous variable is independent of arbitrary cut-off points and produces more explicable results. PMID: 18455370 [PubMed - indexed for MEDLINE]
Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with personality traits in healthy individuals.
Krug A, Markov V, Leube D, Zerres K, Eggermann T, Nöthen MM, Skowronek MH, Rietschel M, Kircher T Related Articles Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with personality traits in healthy individuals. Eur Psychiatry. 2008 Aug;23(5):344-9 Authors: Krug A, Markov V, Leube D, Zerres K, Eggermann T, Nöthen MM, Skowronek MH, Rietschel M, Kircher T BACKGROUND: Differences in personality traits have long been acknowledged as potential risk factors in developing psychiatric disorders. Lately, several susceptibility genes of different psychiatric disorders have been linked to personality traits. This has not been done for schizophrenia yet. Neuregulin1 has been repeatedly shown to be associated with schizophrenia and is involved in numerous neurodevelopmental functions such as neuronal migration and myelination. The impact of this gene might also modulate personality traits in healthy subjects. METHODS: The NRG1 status of 523 healthy subjects was determined with a single nucleotide polymorphism (SNP8NRG221533) which has been described as a tagging marker being part of the core at-risk haplotype for schizophrenia. Genotype was correlated with personality traits using the NEO-FFI questionnaire. RESULTS: Subjects with the NRG1 risk allele scored higher on neuroticism (p<.05) and lower on conscientiousness (p<.05). Further, interactions of genotype by gender for extraversion (p<.05), openness (p<.05) and conscientiousness (p<.05) were found with men carrying the risk allele scoring the lowest. CONCLUSIONS: The data indicate that the NRG1 gene which has found to be associated with schizophrenia may also influence personality differences in healthy subjects. PMID: 18455369 [PubMed - indexed for MEDLINE]
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Brain-Based Therapy with Children and Adolescents: Evidence-Based Treatment for Everyday Practice
John B. Arden, PhD, Lloyd Linford Mon, 17 Nov 2008 05:00:00 -0000
Designed for mental health professionals treating children and adolescents, Brain-Based Therapy with Children and Adolescents: Evidence-Based Treatment for Everyday Practice is a simple but powerful primer for understanding and successfully implementing the most critical elements of neuroscience into an evidence-based mental health practice. Written for counselors, social workers, psychologists, and graduate students, this new treatment approach focuses Read More...
History of Cognitive Neuroscience
M. R. Bennett, P. M. S. Hacker Mon, 17 Nov 2008 05:00:00 -0000
In this companion work to the highly acclaimed Philosophical Foundations of Neuroscience, the distinguished neurophysiologist M. R. Bennett and eminent philosopher P. M. S. Hacker return to the relationship between brain function and our psychological attributes. While their earlier work identified the troubling conceptual issues in contemporary neuroscience, History of Cognitive Neuroscience documents the history of the study of perception and sensation Read More...
Youth, Violence, and Social Disintegration, Number 119
Wilhelm Heitmeyer (Editor), Sandra Hupping (Editor) Mon, 17 Nov 2008 05:00:00 -0000
Read More...
All Psychiatry Jobs
Locum Tenens Psychiatry Job in Government: Great job for a Psychiatrist in Walla Walla, OR. Any state license will work. Washington with CompHealth Inc
Job 0834122-0005 Any active, unrestrictive license Outpatient; Residential Treatment and Substance Abuse Rehab Programs Board Certified or Board Eligible Monday - Friday 8a-4:30p, no call NPI & BLS
Locum Tenens Psychiatry Job in Maryland Client looking for an adult psychiatrist to provide locum tenens in an inpatient setting. Maryland with CompHealth Inc
Job 0118338-0058 Inpatient adult psychiatry; see patient with general psychiatric needs as well as severe mentally ill. General census is 13.5 in a 17 bed unit. Adult psychiatrist - (Locum tenens work)
Locum Tenens Psychiatry Job in WANT SOME GREAT CHEESE? Wisconsin with CompHealth Inc
Job 1466712-0019 VISIT WISCONSIN -- THE "CHEESE" STATE MONDAY - FRIDAY 8:00-5:00 GERI INPATIENT UNIT VERY LOW CASE LOAD CALL NEEDED We offer competitive pay that may include incentives and bonuses We
All Psychiatry Adult Jobs
Permanent Psychiatry Adult Job in Oklahoma City Oklahoma with OUHSC University of Oklahoma Health Services
GENERAL PSYCHIATRIST POSITION The Department of Psychiatry and Behavioral Sciences, University of Oklahoma Health Sciences Center, is recruiting a psychiatrist with interest in a clinician/educator track.
Permanent Psychiatry Adult Job in Plattsburgh New York with CVPH Medical Center
ADIRONDACK MOUNTAINS - LAKE CHAMPLAIN REGION CVPH Medical Center (www.cvph.org) seeks staff adult psychiatrist to do inpatient work. Hospital employed position with call of 1:4. Enjoy working with
Permanent Psychiatry Adult Job in Erie Pennsylvania with Saint Vincent Health Center
Seeking Full-time BC/BE Adult Psychiatrist to join our team of 4 adult Psychiatrists and 2 child Psychiatrists. Ideally, would like someone with an interest in Geriatric Psychiatry for our new Geriatric
Advances in Psychiatric Treatment current issue
[Articles] Psychoanalytic and psychodynamic therapies for depression: the evidence base
Taylor, D. Fri, 31 Oct 2008 00:00:00 -0000
This article argues that the current approach to guideline development for the treatment of depression is not supported by the evidence: clearly depression is not a disease for which treatment efficacy is best determined by short-term randomised controlled trials. As a result, important findings have been marginalised. Different principles of evidence-gathering are described. When a wider range of the available evidence is critically considered the case for dynamic approaches to the treatment of depression can be seen to be stronger than is often thought. Broadly, the benefits of short-term psychodynamic therapies are equivalent in size to the effects of antidepressants and cognitive–behavioural therapy (CBT). The benefits of CBT may occur more quickly, but those of short-term psychodynamic therapies may continue to increase after treatment. There may be a ceiling on the effects of short-term treatments of whatever type. Longer-term psychodynamic treatments may improve associated social, work and personal dysfunctions as well as reductions in depressive symptoms.
[Articles] Gulf War syndrome - has it gone away?
Tarn, M., Greenberg, N., Wessely, S. Fri, 31 Oct 2008 00:00:00 -0000
‘Gulf War syndrome’ was a phrase coined after the 1991 Gulf War. This article looks at the variety of hypotheses that have been put forward about the origins of the concept and the studies attempting to characterise the health manifestations of Gulf service and the lasting effects on veterans. It also serves to bring readers up to date with research on the present deployment in Iraq. Finally, consideration is given to how Gulf War syndrome compares with the rich historical literature of post-conflict medical syndromes and how sociological factors may interact with symptom attribution in veterans.
[Articles] Cannabis use by people with severe mental illness - is it important?
Atakan, Z. Fri, 31 Oct 2008 00:00:00 -0000
Cannabis use is more common among people with severe mental illness than in the general population. It has detrimental effects on the course of the illness, physical health and social life of users, as well as being a financial burden on health services. It is important to understand why some people with severe mental illness continue to use cannabis, despite experiencing its effects on their condition. This article reviews research on the scale of cannabis use by such patients, the effects on the course of their illness, possible reasons to explain why they use it, and how they can be assessed in clinical settings, as well as providing some assessment tools to measure various characteristics related to cannabis use.
Am J Psychiatry current issue
[In This Issue] In this Issue
Mon, 03 Nov 2008 00:00:00 -0000
[Editorials] New Findings on Antipsychotic Use in Children and Adolescents With Schizophrenia Spectrum Disorders
Ross, R. G. Mon, 03 Nov 2008 00:00:00 -0000
[Editorials] Depression, Bereavement, and "Understandable" Intense Sadness: Should the DSM-IV Approach Be Revised?
Maj, M. Mon, 03 Nov 2008 00:00:00 -0000
Archives of General Psychiatry current issue
ABOUT THIS JOURNAL: About This Journal
Mon, 03 Nov 2008 00:00:00 -0000
THIS MONTH IN ARCHIVES OF GENERAL PSYCHIATRY: This Month in Archives of General Psychiatry
Mon, 03 Nov 2008 00:00:00 -0000
ART AND IMAGES IN PSYCHIATRY: The Mothers (VI From Seven Woodcuts to War)
Harris, J. C. Mon, 03 Nov 2008 00:00:00 -0000
Acad Psychiatry current issue
[EDITORIALS] Wise Advice (from an Unlikely Source) for the Profession of Academic Psychiatry
Roberts, L. W. Wed, 22 Oct 2008 00:00:00 -0000
[EDITORIALS] Innovation and Inspiration in Child and Adolescent Psychiatric Education
Beresin, E. Wed, 22 Oct 2008 00:00:00 -0000
[RESEARCH ARTICLES] Increasing Interest in Child and Adolescent Psychiatry in the Third-Year Clerkship: Results from a Post-Clerkship Survey
Malloy, E., Hollar, D., Lindsey, B. A. Wed, 22 Oct 2008 00:00:00 -0000
OBJECTIVE: The authors aimed to determine whether a structured clinical experience in child and adolescent psychiatry (CAP) during the third-year psychiatry clerkship would impact interest in pursuing careers in psychiatry and CAP. METHODS: The authors constructed and administered a postrotation survey, the Child and Adolescent Psychiatry Experiences Questionnaire (CAPE-Q), to evaluate clinical experiences and career interest in psychiatry and CAP both before and after a clerkship in psychiatry. The value of specific aspects of the clerkship to students’ career decisions was also assessed. The students completed the surveys at the end of their psychiatry clerkship in the 2005–2006 academic year and in their first rotation of 2006–2007. RESULTS: Of the 98 respondents, the majority reported no change in interest in general psychiatry or in CAP after the clerkship. However, exposure to inpatient CAP correlated with increased interest in the field and in its influence on pursuing a CAP career. Interest in CAP positively correlated with agreement that the CAP clinical experience influenced their career decision. The influence of the CAP clinical experience on career decision was associated with interest in both psychiatry and CAP, as well as with change in CAP interest after the clerkship. CONCLUSION: These preliminary results suggest that the CAPE-Q may be useful for assessing students’ clerkship experiences and the impact of these experiences on their decision to pursue a career in child psychiatry. Here, inpatient CAP experience led to increased interest in the field. The CAPE-Q could be used to identify students for whom electives and mentoring opportunities could be arranged. It could also be used in assessment of clerkship experiences.
PubMed: 0924-9338
CSF monoamine metabolites and neuropeptides in depressed patients before and after electroconvulsive therapy.
Nikisch G, Mathé AA Related Articles CSF monoamine metabolites and neuropeptides in depressed patients before and after electroconvulsive therapy. Eur Psychiatry. 2008 Aug;23(5):356-9 Authors: Nikisch G, Mathé AA Antidepressant drugs affect monoamines and neuropeptides in human cerebrospinal fluid (CSF) and in rodent brain. The purpose of this study was to investigate if also electroconvulsive therapy (ECT) affects these compounds in a similar manner in the CSF of depressed patients. Homovanillic acid (HVA), 5-hydroxyindoleacetic acid (5-HIAA), and corticotropin-releasing hormone (CRH)-like immunoreactivity (-LI) and neuropeptide Y (NPY)-LI were determined in CSF in six drug resistant patients with major depression. Lumbar puncture was performed at baseline and after completion of eight ECTs. ECT was associated with an increase in NPY-LI (p=0.009) and a decrease in CRH-LI (p<or=0.001). HVA (p=0.003) and 5-HIAA (p=0.002) were significantly increased after the ECT. Findings of NPY increase and CRH decrease were similar to those following chronic treatment with citalopram, indicating that these changes might constitute one of the common underpinnings of antidepressant treatment modalities. PMID: 18455913 [PubMed - indexed for MEDLINE]
Association between age at onset and clinical features of schizophrenia: the Northern Finland 1966 birth cohort study.
Luoma S, Hakko H, Ollinen T, Järvelin MR, Lindeman S Related Articles Association between age at onset and clinical features of schizophrenia: the Northern Finland 1966 birth cohort study. Eur Psychiatry. 2008 Aug;23(5):331-5 Authors: Luoma S, Hakko H, Ollinen T, Järvelin MR, Lindeman S PURPOSE: To study the association between age at onset and the clinical picture of schizophrenia in an unselected young birth cohort. SUBJECTS AND METHODS: The study sample consists of 98 (64 males and 34 females) individuals with DSM-III-R schizophrenia collected from the Northern Finland 1966 birth cohort. Firstly, subjects were divided into very early- and young-onset subgroups by using the median age at onset (22 years in males and 20 in females), as a cut-off point. Secondly, we used age at onset as a continuous variable. Clinical features of schizophrenia were assessed using the Operational Criteria Checklist for Psychotic Illnesses (OCCPI). RESULTS: Inappropriate affect, positive thought disorder and deterioration from premorbid level of function associate with very early-onset schizophrenia, while slowed activity and dysphoria relate to young-onset. These symptoms correlate significantly with the age at onset. DISCUSSION: Differences in the clinical picture associating to the age at onset of schizophrenia are seen early. CONCLUSION: These findings indicate that certain symptoms of schizophrenia are dependent on the age at onset, and schizophrenia occurring initially in early life has some typical features. Using the age at onset as a continuous variable is independent of arbitrary cut-off points and produces more explicable results. PMID: 18455370 [PubMed - indexed for MEDLINE]
Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with personality traits in healthy individuals.
Krug A, Markov V, Leube D, Zerres K, Eggermann T, Nöthen MM, Skowronek MH, Rietschel M, Kircher T Related Articles Genetic variation in the schizophrenia-risk gene neuregulin1 correlates with personality traits in healthy individuals. Eur Psychiatry. 2008 Aug;23(5):344-9 Authors: Krug A, Markov V, Leube D, Zerres K, Eggermann T, Nöthen MM, Skowronek MH, Rietschel M, Kircher T BACKGROUND: Differences in personality traits have long been acknowledged as potential risk factors in developing psychiatric disorders. Lately, several susceptibility genes of different psychiatric disorders have been linked to personality traits. This has not been done for schizophrenia yet. Neuregulin1 has been repeatedly shown to be associated with schizophrenia and is involved in numerous neurodevelopmental functions such as neuronal migration and myelination. The impact of this gene might also modulate personality traits in healthy subjects. METHODS: The NRG1 status of 523 healthy subjects was determined with a single nucleotide polymorphism (SNP8NRG221533) which has been described as a tagging marker being part of the core at-risk haplotype for schizophrenia. Genotype was correlated with personality traits using the NEO-FFI questionnaire. RESULTS: Subjects with the NRG1 risk allele scored higher on neuroticism (p<.05) and lower on conscientiousness (p<.05). Further, interactions of genotype by gender for extraversion (p<.05), openness (p<.05) and conscientiousness (p<.05) were found with men carrying the risk allele scoring the lowest. CONCLUSIONS: The data indicate that the NRG1 gene which has found to be associated with schizophrenia may also influence personality differences in healthy subjects. PMID: 18455369 [PubMed - indexed for MEDLINE]

Sites:
Baylor Department of Psychiatry: Faculty, residency, research, and treatment program links are provided by this university in Texas.Brown University Department of Psychiatry: Offering research, training, faculty, and other psychiatry information from Brown.
Harvard Medical School - Department of Psychiatry: Harvard provides links describing their Mission, Organization, Clinical Services, Research, Education Training, Integrated Programs, and Faculty Affairs.
McMaster University Department of Psychiatry, Canada: McMaster offers many links of interest to current or future psychiatry residents and practicing psychiatrists.
Melbourne - Department of Psychiatry: Department of Psychiatry, The University of Melbourne
New York University Department of Psychiatry: Patient self screening tools, a reference desk, residency topics, and CME are offered.
OHSU Division of Child and Adolescent Psychiatry: Child and adolescent psychiatric evaluation and treatment, and child psychiatry residency training at OHSU's Doernbecher Children's Hospital.
Oxford University Department of Psychiatry: Home page of the Department of Psychiatry
Queensland Centre for Schizophrenia Research: The Queensland Centre for Mental Health Research is a Business Unit within Wolston Park Hospital, and is funded by Queensland Health through West Moreton District Health Services. QCMHR's research encompasses a broad spectrum of sciences, from molecular biology to the broadest level o...
Southern Illinois University Division of Medicine Psychiatry: A description of the Division. Includes the faculty and staff, educational responsibilities, patient access information and educational resources for medical students, residents and other interested parties.
Stanford University Psychiatry Department: Information about the residency (including downloadable application forms), faculty, and the department of psychiatry at Stanford.
Thorn Course (Cheltenham) UK: The Thorn Course is is a Diploma in Integrated Approaches to Psychosis which is accredited by the Thorn Initiative. It is held in Cheltenham, at the University of Gloucestershire.
University of Arizona Department of Psychiatry: Many links about psychiatric research and training.
University of Arkansas Department of Psychiatry: This site contains detailed information for psychiatry residents and also for local patients in need of psychiatric care.
University of British Columbia Department of Psychiatry: The Department of Psychiatry, the Univeristy of British Columbia...
University of California Davis Department of Psychiatry: Site provides information about the department, including information on services provided, faculty, training program, and fellowships.
University of Chicago-Psychiatry: Complete departmental information as well as resources for practitioners, trainees, and patients are found here.
University of Florida, Department of Psychiatry: Residency training, research, and faculty information is provided.
University of Iowa Psychiatry: Home page for UI Health Care, Department of Psychiatry.
University of Maryland Psychiatry Department: Department of Psychiatry
University of Miami-Psychiatry: Psychiatry and Behavioral Sciences Department for the University of Miami, School of Medicine.
University of Michigan Department of Psychiatry: Information about psychiatric education, research, and care at the University of Michigan.
University of Pittsburgh Department of Psychiatry: Department education, research, and clinical care information.
University of South Carolina Department of Psychiatry: Research, residency, faculty, and conference links are provided. Clinical services information for regional patients is also available.
University of Texas at Galveston-Psychiatry: A place where prospective patients can find mental help and a description of the clinical services provided. Other topics include education, research and community services.
University of Texas Southwestern Department of Psychiatry: University of Texas Southwestern Medical Center at Dallas
University of Texas-Houston Psychiatry Department: How to make donations to The University of Texas Medical School Department of Psychiatry and Behavioral Sciences
University of Wisconsin Department of Psychiatry: Residency and faculty information is provided.
Wayne State University, Department of Psychiatry: Psychiatry residency, faculty, research, and clinical services information from this university in Detroit, Michigan.
Yale-Department of Psychiatry: Yale University School of Medicine



