submit url • add directory • nursing jobs
Related Topics:
Medline :: Online DatabasesHealthcare News and Media Publications
Health Journals
Journals :: Optometry
Vision Impairments :: Magazines and E zines
Today's News:
Archives of Ophthalmology current issue
About This Journal [About This Journal]
Progression of Age-Related Macular Degeneration After Cataract Surgery [Clinical Sciences]
Dong, L. M., Stark, W. J., Jefferys, J. L., Al-Hazzaa, S., Bressler, S. B., Solomon, S. D., Bressler, N. M. Objective To document age-related macular degeneration (AMD) progression after cataract surgery. Methods Surgeons prospectively enrolled patients with nonneovascular AMD who were awaiting cataract surgery. Fluorescein angiography was performed preoperatively and at the postoperative week 1, month 3, and month 12 visits. Incidence of neovascular AMD development within 12 months after operation was the primary outcome measure. Results A total of 108 subjects were enrolled. Of 86 eyes with preoperatively photographically confirmed nonneovascular AMD, 71 had gradable images by month 12. Neovascular AMD was observed in 9 of 71 eyes (12.7%; 95% confidence interval, 6.0%-22.7%). The progression rate between week 1 and month 12 decreased to 3 of 65 eyes (4.6%; 95% confidence interval, 1.0%-12.9%) after excluding 5 neovascular events identified on the postoperative week 1 visit and 1 case with missing photographs at this visit. Conclusion The low incidence rate of neovascular AMD development between 1 week and 1 year after cataract surgery did not support the hypothesis that cataract surgery increases the risk of AMD progression. Several eyes appeared to have disease progression on postsurgery week 1 fluorescein angiograms, suggesting that many cases of presumed progression to neovascular AMD following cataract surgery may have been present prior to cataract surgery, but not recognized owing to lens opacity.
Corneal Endothelial Cell Loss 9 Years After Excimer Laser Keratorefractive Surgery [Clinical Sciences]
Patel, S. V., Bourne, W. M. Objective To determine the long-term changes in the corneal endothelium after laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK). Methods Twenty-nine eyes (16 patients) received myopic LASIK or PRK, with intended correction to emmetropia. Central endothelial photographs were taken before and 9 years after surgery and were analyzed by the same masked investigator after appropriate calibration for magnification. Comparisons were made by using generalized estimating equation models to account for any correlation between fellow eyes of the same patient. The annual exponential rate of cell loss was compared with cell loss during a 10-year period in 42 normal (unoperated) corneas of 42 subjects. Results Endothelial cell density 9 years after LASIK and PRK had decreased by 5.3% from preoperative density (P < .001), whereas coefficient of variation of cell area (P = .24) and percentage of hexagonal cells (P = .19) did not change. The mean annual rate of cell loss after refractive surgery (0.6% [standard deviation, 0.8%]) was not different from that in normal corneas (0.6% [0.5%], P = .88; minimum detectable difference = 0.5%; = .05; β = .20). Conclusions Laser in situ keratomileusis and PRK had no long-term effect on the corneal endothelium. Corneas that have undergone LASIK or PRK can be considered for use as donors for posterior lamellar keratoplasty procedures.
Long-term Outcomes of Keratolimbal Allograft for Total Limbal Stem Cell Deficiency Using Combined Immunosuppressive Agents and Correction of Ocular Surface Deficits [Clinical Sciences]
Liang, L., Sheha, H., Tseng, S. C. G. Objective To determine the long-term outcomes of keratolimbal allograft (KLAL). Methods Scores of such risks as infrequent blinking, blink-related microtrauma, conjunctival inflammation, elevated intraocular pressure, dry eye, symblepharon, lagophthalmos, and previous KLAL or penetrating keratoplasty (PKP) failure were calculated and recorded before, during, and after KLAL. Prolonged oral mycophenolate mofetil and tacrolimus and short-term prednisone and acyclovir were administered in 12 eyes (10 consecutive patients) with total limbal stem cell deficiency after KLAL. Ten eyes underwent subsequent PKP. Results More corrective measures were required in eyes with higher risk scores. During a follow-up of 61.2 months (standard deviation [SD], 18.2; range, 36-91 months) after KLAL, postoperative epithelial breakdown due to exposure occurred late in the period after PKP and remained a primary risk. Mean daily doses of 1.4 g of mycophenolate mofetil and 1.6 mg of tacrolimus were administered for 52.7 months (SD, 22.5; range, 23-91 months) with few adverse effects and reached trough levels of 1.6 µg/mL (SD, 0.6 µg/mL) and 4.5 ng/mL (SD, 2 ng/mL), respectively. Keratolimbal allograft and PKP rejection was noted in 2 and 3 eyes, respectively, though there was a reversal in 1 eye in each group, yielding final KLAL and PKP survivals in 10 and 8 eyes, respectively, and ambulatory visual acuity of up to 20/20 in 10 eyes for 67.2% of the entire follow-up period. Conclusion Correction of ocular surface deficits combined with an immunosuppressive regimen further improves the long-term outcome of KLAL in eyes with total limbal stem cell deficiency.
Outcomes of Ahmed Glaucoma Valve Implantation in Children With Primary Congenital Glaucoma [Clinical Sciences]
Ou, Y., Yu, F., Law, S. K., Coleman, A. L., Caprioli, J. Objectives To evaluate the long-term efficacy of intraocular pressure reduction and complications of Ahmed glaucoma valve (AGV) implantation in children with primary congenital glaucoma. Methods The medical records of patients with primary congenital glaucoma who underwent AGV implantation with a minimum follow-up of 6 months were reviewed. The primary outcome measure was cumulative probability of success, defined as intraocular pressure greater than 5 mm Hg and less than 23 mm Hg and at least a 15% reduction from the preoperative intraocular pressure, without serious complications, additional glaucoma surgery, or loss of light perception. Results Thirty eyes of 19 children with primary congenital glaucoma who underwent AGV implantation with a minimum follow-up of 6 months were reviewed. The children had a mean (SD) age of 1.8 (2.6) years, a mean (SD) preoperative intraocular pressure of 28.4 (6.7) mm Hg, and a mean (SD) follow-up time of 57.6 (48.0) months. The cumulative probability of success was 63% in 1 year and 33% in 5 years. After a second AGV implantation, the cumulative probability of success was 86% in 1 and 2 years and 69% in 5 years. Hispanic ethnicity (P = .02) and being female (P = .005) were associated with increased risk of failure. Conclusions Thirty-three percent of AGV implantations in children with primary congenital glaucoma were successful after 5 years of follow-up. With the implantation of a second AGV, the 5-year success rate increased to 69%.
Diffuse Glaucomatous Structural and Functional Damage in the Hemifield Without Significant Pattern Loss [Clinical Sciences]
Grewal, D. S., Sehi, M., Greenfield, D. S. Objectives To compare the retinal nerve fiber layer (RNFL) thickness and retinal sensitivity in the normal visual hemifield of glaucomatous eyes with localized visual field loss with those of normal eyes and eyes with suspected glaucoma, and to evaluate the relationship between RNFL atrophy and glaucoma severity. Methods One randomly selected eye of each subject underwent standard automated perimetry, stereoscopic photography, scanning laser polarimetry with enhanced corneal compensation, and time-domain and spectral-domain optical coherence tomography (OCT). Mean retinal sensitivity values were calculated in the normal standard automated perimetry hemifield of the glaucoma group and randomly selected hemifields in the normal and suspected glaucoma groups. The mean RNFL thickness values corresponding to the normal hemifield were calculated. Glaucoma severity was judged using standard automated perimetry pattern standard deviation and the Heidelberg retina tomograph–derived linear cup-disc ratio. Results Fifty subjects were enrolled in each group. Mean RNFL thickness in the normal hemifield obtained using spectral-domain OCT, time-domain OCT, and scanning laser polarimetry with enhanced corneal compensation was significantly (P ≤ .01) thinner in the glaucoma group compared with the normal and suspected glaucoma groups. Mean retinal sensitivity in the normal hemifield was significantly (P < .001) reduced in the glaucoma group compared with the normal and suspected glaucoma groups. The Heidelberg retina tomograph–derived cup-disc ratio was significantly correlated with mean RNFL thickness in the normal hemifield obtained using spectral-domain OCT, time-domain OCT, and scanning laser polarimetry with enhanced corneal compensation (P ≤ .01). Conclusions Diffuse RNFL atrophy and retinal sensitivity loss exist in glaucomatous eyes with localized standard automated perimetry deficits. Glaucomatous damage affects both structure and function in a linear proportion.
Subscribe to Journals RSS feed 
About This Journal [About This Journal]
Progression of Age-Related Macular Degeneration After Cataract Surgery [Clinical Sciences]
Dong, L. M., Stark, W. J., Jefferys, J. L., Al-Hazzaa, S., Bressler, S. B., Solomon, S. D., Bressler, N. M. Objective To document age-related macular degeneration (AMD) progression after cataract surgery. Methods Surgeons prospectively enrolled patients with nonneovascular AMD who were awaiting cataract surgery. Fluorescein angiography was performed preoperatively and at the postoperative week 1, month 3, and month 12 visits. Incidence of neovascular AMD development within 12 months after operation was the primary outcome measure. Results A total of 108 subjects were enrolled. Of 86 eyes with preoperatively photographically confirmed nonneovascular AMD, 71 had gradable images by month 12. Neovascular AMD was observed in 9 of 71 eyes (12.7%; 95% confidence interval, 6.0%-22.7%). The progression rate between week 1 and month 12 decreased to 3 of 65 eyes (4.6%; 95% confidence interval, 1.0%-12.9%) after excluding 5 neovascular events identified on the postoperative week 1 visit and 1 case with missing photographs at this visit. Conclusion The low incidence rate of neovascular AMD development between 1 week and 1 year after cataract surgery did not support the hypothesis that cataract surgery increases the risk of AMD progression. Several eyes appeared to have disease progression on postsurgery week 1 fluorescein angiograms, suggesting that many cases of presumed progression to neovascular AMD following cataract surgery may have been present prior to cataract surgery, but not recognized owing to lens opacity.
Corneal Endothelial Cell Loss 9 Years After Excimer Laser Keratorefractive Surgery [Clinical Sciences]
Patel, S. V., Bourne, W. M. Objective To determine the long-term changes in the corneal endothelium after laser in situ keratomileusis (LASIK) and photorefractive keratectomy (PRK). Methods Twenty-nine eyes (16 patients) received myopic LASIK or PRK, with intended correction to emmetropia. Central endothelial photographs were taken before and 9 years after surgery and were analyzed by the same masked investigator after appropriate calibration for magnification. Comparisons were made by using generalized estimating equation models to account for any correlation between fellow eyes of the same patient. The annual exponential rate of cell loss was compared with cell loss during a 10-year period in 42 normal (unoperated) corneas of 42 subjects. Results Endothelial cell density 9 years after LASIK and PRK had decreased by 5.3% from preoperative density (P < .001), whereas coefficient of variation of cell area (P = .24) and percentage of hexagonal cells (P = .19) did not change. The mean annual rate of cell loss after refractive surgery (0.6% [standard deviation, 0.8%]) was not different from that in normal corneas (0.6% [0.5%], P = .88; minimum detectable difference = 0.5%; = .05; β = .20). Conclusions Laser in situ keratomileusis and PRK had no long-term effect on the corneal endothelium. Corneas that have undergone LASIK or PRK can be considered for use as donors for posterior lamellar keratoplasty procedures.
Long-term Outcomes of Keratolimbal Allograft for Total Limbal Stem Cell Deficiency Using Combined Immunosuppressive Agents and Correction of Ocular Surface Deficits [Clinical Sciences]
Liang, L., Sheha, H., Tseng, S. C. G. Objective To determine the long-term outcomes of keratolimbal allograft (KLAL). Methods Scores of such risks as infrequent blinking, blink-related microtrauma, conjunctival inflammation, elevated intraocular pressure, dry eye, symblepharon, lagophthalmos, and previous KLAL or penetrating keratoplasty (PKP) failure were calculated and recorded before, during, and after KLAL. Prolonged oral mycophenolate mofetil and tacrolimus and short-term prednisone and acyclovir were administered in 12 eyes (10 consecutive patients) with total limbal stem cell deficiency after KLAL. Ten eyes underwent subsequent PKP. Results More corrective measures were required in eyes with higher risk scores. During a follow-up of 61.2 months (standard deviation [SD], 18.2; range, 36-91 months) after KLAL, postoperative epithelial breakdown due to exposure occurred late in the period after PKP and remained a primary risk. Mean daily doses of 1.4 g of mycophenolate mofetil and 1.6 mg of tacrolimus were administered for 52.7 months (SD, 22.5; range, 23-91 months) with few adverse effects and reached trough levels of 1.6 µg/mL (SD, 0.6 µg/mL) and 4.5 ng/mL (SD, 2 ng/mL), respectively. Keratolimbal allograft and PKP rejection was noted in 2 and 3 eyes, respectively, though there was a reversal in 1 eye in each group, yielding final KLAL and PKP survivals in 10 and 8 eyes, respectively, and ambulatory visual acuity of up to 20/20 in 10 eyes for 67.2% of the entire follow-up period. Conclusion Correction of ocular surface deficits combined with an immunosuppressive regimen further improves the long-term outcome of KLAL in eyes with total limbal stem cell deficiency.
Outcomes of Ahmed Glaucoma Valve Implantation in Children With Primary Congenital Glaucoma [Clinical Sciences]
Ou, Y., Yu, F., Law, S. K., Coleman, A. L., Caprioli, J. Objectives To evaluate the long-term efficacy of intraocular pressure reduction and complications of Ahmed glaucoma valve (AGV) implantation in children with primary congenital glaucoma. Methods The medical records of patients with primary congenital glaucoma who underwent AGV implantation with a minimum follow-up of 6 months were reviewed. The primary outcome measure was cumulative probability of success, defined as intraocular pressure greater than 5 mm Hg and less than 23 mm Hg and at least a 15% reduction from the preoperative intraocular pressure, without serious complications, additional glaucoma surgery, or loss of light perception. Results Thirty eyes of 19 children with primary congenital glaucoma who underwent AGV implantation with a minimum follow-up of 6 months were reviewed. The children had a mean (SD) age of 1.8 (2.6) years, a mean (SD) preoperative intraocular pressure of 28.4 (6.7) mm Hg, and a mean (SD) follow-up time of 57.6 (48.0) months. The cumulative probability of success was 63% in 1 year and 33% in 5 years. After a second AGV implantation, the cumulative probability of success was 86% in 1 and 2 years and 69% in 5 years. Hispanic ethnicity (P = .02) and being female (P = .005) were associated with increased risk of failure. Conclusions Thirty-three percent of AGV implantations in children with primary congenital glaucoma were successful after 5 years of follow-up. With the implantation of a second AGV, the 5-year success rate increased to 69%.
Diffuse Glaucomatous Structural and Functional Damage in the Hemifield Without Significant Pattern Loss [Clinical Sciences]
Grewal, D. S., Sehi, M., Greenfield, D. S. Objectives To compare the retinal nerve fiber layer (RNFL) thickness and retinal sensitivity in the normal visual hemifield of glaucomatous eyes with localized visual field loss with those of normal eyes and eyes with suspected glaucoma, and to evaluate the relationship between RNFL atrophy and glaucoma severity. Methods One randomly selected eye of each subject underwent standard automated perimetry, stereoscopic photography, scanning laser polarimetry with enhanced corneal compensation, and time-domain and spectral-domain optical coherence tomography (OCT). Mean retinal sensitivity values were calculated in the normal standard automated perimetry hemifield of the glaucoma group and randomly selected hemifields in the normal and suspected glaucoma groups. The mean RNFL thickness values corresponding to the normal hemifield were calculated. Glaucoma severity was judged using standard automated perimetry pattern standard deviation and the Heidelberg retina tomograph–derived linear cup-disc ratio. Results Fifty subjects were enrolled in each group. Mean RNFL thickness in the normal hemifield obtained using spectral-domain OCT, time-domain OCT, and scanning laser polarimetry with enhanced corneal compensation was significantly (P ≤ .01) thinner in the glaucoma group compared with the normal and suspected glaucoma groups. Mean retinal sensitivity in the normal hemifield was significantly (P < .001) reduced in the glaucoma group compared with the normal and suspected glaucoma groups. The Heidelberg retina tomograph–derived cup-disc ratio was significantly correlated with mean RNFL thickness in the normal hemifield obtained using spectral-domain OCT, time-domain OCT, and scanning laser polarimetry with enhanced corneal compensation (P ≤ .01). Conclusions Diffuse RNFL atrophy and retinal sensitivity loss exist in glaucomatous eyes with localized standard automated perimetry deficits. Glaucomatous damage affects both structure and function in a linear proportion.
Sites:
Anterior Eye: A research-based journal covering all aspects of contact lens theory and practice.Acta Ophthalmologica Scandinavica: Acta Ophthalmologica Scandinavica: journal information, contents lists and abstracts on the Blackwell Publishing website.
American Journal of Ophthalmology: Monthly peer reviewed scientific publication for ophthalmologists.
American Orthoptic Journal: The journal serves as a forum for orthoptists and ophthalmologists to present new material in the fields of amblyopia and strabismus. Members of the orthoptic and ophthalmological communities can keep abreast of current clinical practice and research in the field of ocular motility.
Archives of Ophthalmology: Archives of Ophthalmology is a monthly professional medical journal published by the American Medical Association. Archives of Ophthalmology publishes peer-reviewed, original articles on such topics as epidemiology and biostatistics, mechanisms of ophthalmic disease, ophthalmic molecular genetics...
Asian Journal of Ophthalmology: The Asian Journal of OPHTHALMOLOGY is a quarterly publication for the practising ophthalmologist. As new technologies and therapeutic interventions are continually being developed, ophthalmology has become a field of rapid change, particularly in the Asia-Pacific region, where disease patterns an...
BMC Ophthalmology: Open access, peer-reviewed journal that considers articles on all aspects of eye disorders, and related molecular genetics, pathophysiology, and epidemiology.
British Journal of Ophthalmolgy: Journal of Clinical Pathology, a peer review journal for health professionals and researchers in all areas of clinical and molecular pathology
British Journal of Visual Impairment: For professionals concerned with children/adults with visual impairments.
Canadian Journal of Ophthalmology: Official publication of the Canadian Ophthalmological Society.
CLAO Journal: Official publication of the Contact Lens Association of Ophthalmologists.
Clinical and Experimental Ophthalmology: Clinical and Experimental Ophthalmology: journal information, contents lists and abstracts on the Blackwell Publishing website.
Community Eye Health Journal: Home page
Contact Lens Spectrum: Explores the preliminary evaluation of prospective contact lens patients.
Core Journals in Ophthalmology: Each issue contains abstracts of selected clinical articles from the 10-14 most important international specialist journals in the field.
Cornea: Deals with cornea and ocular surface disorders.
Current Eye Research: Publishes articles encompassing all the areas of eye research.
Current Opinion in Ophthalmology: Website provides access to full-text content, online-only content, features and services, author submission materials and title-specific information. An LWWonline partner.
Documenta Ophthalmologica: Bringing basic as well as clinical research on visual electrophysiology.
Electronic Journals: Journal listings in the subject of Optometry, Ophthalmology and Vision Science from UC Berkley Library.
European Journal of Ophthalmology: Clinical and basic research in ophthalmology. It offers detailed charts and graphs, plus high quality illustrations and photographs.
Evidence-Based Eye Care: Website provides access to full-text content, online-only content, features and services, author submission materials and title-specific information. An LWWonline partner.
Experimental Eye Research: Publish original research papers on all aspects of basic experimental sciences related to the eye.
Eye: Eye is the official journal of the Royal College of Ophthalmologists. It aims to provide the practising ophthalmologist with information on the latest clinical and laboratory-based research.
Graefe's Archive for Clinical and Experimental Ophthalmology: Graefe's Archive for Clinical and Experimental Ophthalmology - Ophthalmology. "Graefe's Archive" is a distinguished international journal that presents original clinical reports and clinically relevant experiment...
Greek Annuals of Ophthalmology: The Hellenic Ophthalmological Society is the official association of ophthalmologists in Greece
Indian Journal of Ophthalmology: Official scientific journal of the All India Ophthalmological Society (AIOS)
International Contact Lens Clinic: Devoted to contact lens practitioners.
International Ophthalmology: International Ophthalmology - Ophthalmology. International Ophthalmology provides the clinician with articles on all the relevant subspecialties of ophthalmology, with a broad international scope. In addition to original research pa...
International Ophthalmology Clinics: Updates and reviews on common eye topics.
Investigative Ophthalmology and Visual Science: Web site for Investigative Ophthalmology & Visual Science.
Japanese Journal of Ophthalmology: Journal of the Japanese Ophthalmological Society.
Journal of AAPOS: Presents expert information on children's eye diseases and on strabismus as it impacts all age groups. Official publication of the American Association for Pediatric Ophthalmology and Strabismus.
Journal of Biomedical Optics: Repository for peer-reviewed papers that utilize modern optical technology for improved health care and biomedical research.
Journal of Cataract and Refractive Surgery: Deals all about updates in cataract and refractive disorders.
Journal of Glaucoma: Discussion of clinical, scientific, and socioeconomic issues for glaucoma specialists.
Journal of Neuro-Ophthalmology: Reports on recent developments in diagnosing and treating conditions affecting the oculomotor and visual systems.
Journal of Ocular Pharmacology and Therapeutics: Research on all aspects of drug activity pertaining to preventing or controlling diseases of the eye.
Journal of Ophthalmic Photography: Official publication of the Ophthalmic Photographers' Society.
Journal of Pediatric Ophthalmology and Strabismus: Bimonthly forum for peer-reviewed information useful to the pediatric ophthalmologist.
Journal of Refractive Surgery: The official bimonthly publication of the International Society of Refractive Surgery.
MedBioWorld: Links to Ophthalmology Journals
Neuro-Ophthalmology: A journal of clinical and fundamental research relating to all aspects of neuro-ophthalmology.
Ocular Immunology and Inflammation: Peer reviewed papers pertaining to basic and clinical research on the ocular inflammatory response and its control by the immune system.
Ocular Surgery News International Edition: The Voice of Ophthalmology - latest news and articles from Ocular Surgery News; Ophthalmic Surgery, Lasers and Imaging; Journal of Refractive Surgery; and Pediatric Ophthalmology and Strabismus
Ophthalmic Epidemiology: The official publication of the International Society of Geographical and Epidemiological Ophthalmology.
Ophthalmic Genetics: The official publication of the International Society for Genetic Eye Disease, the European Paediatric Ophthalmology Society and the Ophthalmic Genetics Study Club.
Ophthalmic Plastic and Reconstructive Surgery: Website provides access to full-text content, online-only content, features and services, author submission materials and title-specific information. An LWWonline partner.
Ophthalmic Research: Features original papers and reviews reporting basic and clinical experimental studies.
Ophthalmic Surgery, Lasers and Imaging: Deals with aspects of ophthalmic surgery, laser technology, ocular imaging and treatment.
Ophthalmologica: Guide to international work in clinical and experimental ophthalmology.
Ophthalmology: Journal of the American Academy of Ophthalmology.
Ophthalmology Clinics of North America: Presents newest advances and a sound basis for choosing treatment options. Each issue focuses on a single topic presented under the direction of an experienced guest editor.
Ophthalmology Management: Publication designed to give practicing ophthalmologists the business savvy they need in the areas of finance, contract negotiation and practice management. A monthly advisor guiding MDs and practice administrators toward a more successful practice.
Ophthalmology Review Journal: Five years of the journal arranged by subject.
Ophthalmology Times: Physician-driven publication that disseminates news and information of a clinical, socioeconomic, and political nature.
Orbit: The international journal on orbital disorders, oculoplastic and lacrimal surgery.
Primary Care Optometry News: Full text articles and online seminar with special forum.
Progress in Retinal and Eye Research: Covers all basic and clinical aspects of the eye research.
Retina: Resource for the dissemination of information to retinal and vitreous specialists.
Review of Ophthalmology: Monthly journal publishes review articles about eye disease.
Seminars in Ophthalmology: Offers current, clinically oriented reviews on the diagnosis and treatment of ophthalmic disorders. Each issue focuses on a single topic, with a primary emphasis on appropriate surgical techniques.
Strabismus: Publishes articles related to squint and related disorders.
Survey of Ophthalmology: Surveying major reviews on essential topics and historical articles.
Video Journal of Ophthalmology: Published quarterly and contains video articles on various subjects affecting the clinical, surgical practice of the ophthalmologist.
Vision Research: An international journal for functional aspects of vision.
Visual Impairment Research: The official publication of the International Society for Low-vision Research and Rehabilitation.
This directory is based on the Open Directory and may have been modified
