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American Journal of Epidemiology - current issue
Cover
Editorial Board
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Table of contents
Prediction of Incident Stroke Events Based on Retinal Vessel Caliber: A Systematic Review and Individual-Participant Meta-Analysis
McGeechan, K., Liew, G., Macaskill, P., Irwig, L., Klein, R., Klein, B. E. K., Wang, J. J., Mitchell, P., Vingerling, J. R., de Jong, P. T. V. M., Witteman, J. C. M., Breteler, M. M. B., Shaw, J., Zimmet, P., Wong, T. Y. The caliber of the retinal vessels has been shown to be associated with stroke events. However, the consistency and magnitude of association, and the changes in predicted risk independent of traditional risk factors, are unclear. To determine the association between retinal vessel caliber and the risk of stroke events, the investigators combined individual data from 20,798 people, who were free of stroke at baseline, in 6 cohort studies identified from a search of the Medline (National Library of Medicine, Bethesda, Maryland) and EMBASE (Elsevier B.V., Amsterdam, the Netherlands) databases. During follow-up of 5–12 years, 945 (4.5%) incident stroke events were recorded. Wider retinal venular caliber predicted stroke (pooled hazard ratio = 1.15, 95% confidence interval: 1.05, 1.25 per 20-µm increase in caliber), but the caliber of retinal arterioles was not associated with stroke (pooled hazard ratio = 1.00, 95% confidence interval: 0.92, 1.08). There was weak evidence of heterogeneity in the hazard ratio for retinal venular caliber, which may be attributable to differences in follow-up strategies across studies. Inclusion of retinal venular caliber in prediction models containing traditional stroke risk factors reassigned 10.1% of people at intermediate risk into different, mostly lower, risk categories.
The Quality of Meta-Analyses of Genetic Association Studies: A Review With Recommendations
Minelli, C., Thompson, J. R., Abrams, K. R., Thakkinstian, A., Attia, J. Although there has been a rapid rise in the publication of meta-analyses of genetic association studies, little is known about their methodological quality. The authors reviewed the quality of 120 randomly selected genetic meta-analyses published between 2005 and 2007. Data extracted included issues of general relevance and other issues specific to genetic epidemiology. Quality was markedly poorer in the 26% of the meta-analyses that accompanied a report on a primary study. Such meta-analyses were predominantly published in specialist journals, and their quality was positively associated with the impact factor of the journal. Among the meta-analyses that did not accompany a primary study, Human Genome Epidemiology reviews tended to score better than the others, although the comparison was limited by relatively small numbers. Comparison of the overall quality with that of genetic meta-analyses published before 2000 showed improvement in both conduct and reporting. However, the quality of the handling of specific genetic issues remains disappointingly low. For a few key general quality issues, the authors compared their findings with findings in other fields of medicine and found that general quality was similar. On the basis of this review, the authors provide practical recommendations for the conduct and reporting of genetic meta-analyses.
American Journal of Epidemiology - recent issues
Cover
Editorial Board
Subscriptions
Table of contents
Prediction of Incident Stroke Events Based on Retinal Vessel Caliber: A Systematic Review and Individual-Participant Meta-Analysis
McGeechan, K., Liew, G., Macaskill, P., Irwig, L., Klein, R., Klein, B. E. K., Wang, J. J., Mitchell, P., Vingerling, J. R., de Jong, P. T. V. M., Witteman, J. C. M., Breteler, M. M. B., Shaw, J., Zimmet, P., Wong, T. Y. The caliber of the retinal vessels has been shown to be associated with stroke events. However, the consistency and magnitude of association, and the changes in predicted risk independent of traditional risk factors, are unclear. To determine the association between retinal vessel caliber and the risk of stroke events, the investigators combined individual data from 20,798 people, who were free of stroke at baseline, in 6 cohort studies identified from a search of the Medline (National Library of Medicine, Bethesda, Maryland) and EMBASE (Elsevier B.V., Amsterdam, the Netherlands) databases. During follow-up of 5–12 years, 945 (4.5%) incident stroke events were recorded. Wider retinal venular caliber predicted stroke (pooled hazard ratio = 1.15, 95% confidence interval: 1.05, 1.25 per 20-µm increase in caliber), but the caliber of retinal arterioles was not associated with stroke (pooled hazard ratio = 1.00, 95% confidence interval: 0.92, 1.08). There was weak evidence of heterogeneity in the hazard ratio for retinal venular caliber, which may be attributable to differences in follow-up strategies across studies. Inclusion of retinal venular caliber in prediction models containing traditional stroke risk factors reassigned 10.1% of people at intermediate risk into different, mostly lower, risk categories.
The Quality of Meta-Analyses of Genetic Association Studies: A Review With Recommendations
Minelli, C., Thompson, J. R., Abrams, K. R., Thakkinstian, A., Attia, J. Although there has been a rapid rise in the publication of meta-analyses of genetic association studies, little is known about their methodological quality. The authors reviewed the quality of 120 randomly selected genetic meta-analyses published between 2005 and 2007. Data extracted included issues of general relevance and other issues specific to genetic epidemiology. Quality was markedly poorer in the 26% of the meta-analyses that accompanied a report on a primary study. Such meta-analyses were predominantly published in specialist journals, and their quality was positively associated with the impact factor of the journal. Among the meta-analyses that did not accompany a primary study, Human Genome Epidemiology reviews tended to score better than the others, although the comparison was limited by relatively small numbers. Comparison of the overall quality with that of genetic meta-analyses published before 2000 showed improvement in both conduct and reporting. However, the quality of the handling of specific genetic issues remains disappointingly low. For a few key general quality issues, the authors compared their findings with findings in other fields of medicine and found that general quality was similar. On the basis of this review, the authors provide practical recommendations for the conduct and reporting of genetic meta-analyses.
Epidemiology and Infection - Current Issue
Volume 137 Issue 12
Tue, 01 Dec 2009 00:00:00 -0000
Epidemiology and Infection, Volume 137 Issue 12 Increased frequency in 2007 - now 8 issues per year! Epidemiology and Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The field covered is broad and includes the zoonoses, tropical infections, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease. Papers covering microbiology and immunology which have an epidemiological relevance are part of this broad field. Papers come from medical and veterinary scientists worldwide. It has become the key periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections, will be of particular value. To celebrate 100 years of the journal, a series of important papers has been selected and each, together with a modern commentary on the paper by an expert, will be published on-line. This journal has now moved over to electronic submission, using the Scholar One system. Click here to go to the submission website. Guidance on how to upload your manuscript is available on the site by clicking "User Tutorials". Online manuscript submission (now) available, please go to http://mc.manuscriptcentral.com/cup/hyg
HYG volume 137 issue 12 Cover and Front matter
Miscellaneous Epidemiology and Infection, Volume 137 Issue 12 , pp f1-f2Abstract
Latest Issue of International Journal of Medical Microbiology
Editorial - ETOX turned twenty
Sebo P.
Pathogenomics of mobile genetic elements of toxigenic bacteria
Hacker J.Hochhut B.Middendorf B.Schneider G.Buchrieser C.Gottschalk G.Dobrindt U.
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Cover
Editorial Board
Subscriptions
Table of contents
Prediction of Incident Stroke Events Based on Retinal Vessel Caliber: A Systematic Review and Individual-Participant Meta-Analysis
McGeechan, K., Liew, G., Macaskill, P., Irwig, L., Klein, R., Klein, B. E. K., Wang, J. J., Mitchell, P., Vingerling, J. R., de Jong, P. T. V. M., Witteman, J. C. M., Breteler, M. M. B., Shaw, J., Zimmet, P., Wong, T. Y. The caliber of the retinal vessels has been shown to be associated with stroke events. However, the consistency and magnitude of association, and the changes in predicted risk independent of traditional risk factors, are unclear. To determine the association between retinal vessel caliber and the risk of stroke events, the investigators combined individual data from 20,798 people, who were free of stroke at baseline, in 6 cohort studies identified from a search of the Medline (National Library of Medicine, Bethesda, Maryland) and EMBASE (Elsevier B.V., Amsterdam, the Netherlands) databases. During follow-up of 5–12 years, 945 (4.5%) incident stroke events were recorded. Wider retinal venular caliber predicted stroke (pooled hazard ratio = 1.15, 95% confidence interval: 1.05, 1.25 per 20-µm increase in caliber), but the caliber of retinal arterioles was not associated with stroke (pooled hazard ratio = 1.00, 95% confidence interval: 0.92, 1.08). There was weak evidence of heterogeneity in the hazard ratio for retinal venular caliber, which may be attributable to differences in follow-up strategies across studies. Inclusion of retinal venular caliber in prediction models containing traditional stroke risk factors reassigned 10.1% of people at intermediate risk into different, mostly lower, risk categories.
The Quality of Meta-Analyses of Genetic Association Studies: A Review With Recommendations
Minelli, C., Thompson, J. R., Abrams, K. R., Thakkinstian, A., Attia, J. Although there has been a rapid rise in the publication of meta-analyses of genetic association studies, little is known about their methodological quality. The authors reviewed the quality of 120 randomly selected genetic meta-analyses published between 2005 and 2007. Data extracted included issues of general relevance and other issues specific to genetic epidemiology. Quality was markedly poorer in the 26% of the meta-analyses that accompanied a report on a primary study. Such meta-analyses were predominantly published in specialist journals, and their quality was positively associated with the impact factor of the journal. Among the meta-analyses that did not accompany a primary study, Human Genome Epidemiology reviews tended to score better than the others, although the comparison was limited by relatively small numbers. Comparison of the overall quality with that of genetic meta-analyses published before 2000 showed improvement in both conduct and reporting. However, the quality of the handling of specific genetic issues remains disappointingly low. For a few key general quality issues, the authors compared their findings with findings in other fields of medicine and found that general quality was similar. On the basis of this review, the authors provide practical recommendations for the conduct and reporting of genetic meta-analyses.
American Journal of Epidemiology - recent issues
Cover
Editorial Board
Subscriptions
Table of contents
Prediction of Incident Stroke Events Based on Retinal Vessel Caliber: A Systematic Review and Individual-Participant Meta-Analysis
McGeechan, K., Liew, G., Macaskill, P., Irwig, L., Klein, R., Klein, B. E. K., Wang, J. J., Mitchell, P., Vingerling, J. R., de Jong, P. T. V. M., Witteman, J. C. M., Breteler, M. M. B., Shaw, J., Zimmet, P., Wong, T. Y. The caliber of the retinal vessels has been shown to be associated with stroke events. However, the consistency and magnitude of association, and the changes in predicted risk independent of traditional risk factors, are unclear. To determine the association between retinal vessel caliber and the risk of stroke events, the investigators combined individual data from 20,798 people, who were free of stroke at baseline, in 6 cohort studies identified from a search of the Medline (National Library of Medicine, Bethesda, Maryland) and EMBASE (Elsevier B.V., Amsterdam, the Netherlands) databases. During follow-up of 5–12 years, 945 (4.5%) incident stroke events were recorded. Wider retinal venular caliber predicted stroke (pooled hazard ratio = 1.15, 95% confidence interval: 1.05, 1.25 per 20-µm increase in caliber), but the caliber of retinal arterioles was not associated with stroke (pooled hazard ratio = 1.00, 95% confidence interval: 0.92, 1.08). There was weak evidence of heterogeneity in the hazard ratio for retinal venular caliber, which may be attributable to differences in follow-up strategies across studies. Inclusion of retinal venular caliber in prediction models containing traditional stroke risk factors reassigned 10.1% of people at intermediate risk into different, mostly lower, risk categories.
The Quality of Meta-Analyses of Genetic Association Studies: A Review With Recommendations
Minelli, C., Thompson, J. R., Abrams, K. R., Thakkinstian, A., Attia, J. Although there has been a rapid rise in the publication of meta-analyses of genetic association studies, little is known about their methodological quality. The authors reviewed the quality of 120 randomly selected genetic meta-analyses published between 2005 and 2007. Data extracted included issues of general relevance and other issues specific to genetic epidemiology. Quality was markedly poorer in the 26% of the meta-analyses that accompanied a report on a primary study. Such meta-analyses were predominantly published in specialist journals, and their quality was positively associated with the impact factor of the journal. Among the meta-analyses that did not accompany a primary study, Human Genome Epidemiology reviews tended to score better than the others, although the comparison was limited by relatively small numbers. Comparison of the overall quality with that of genetic meta-analyses published before 2000 showed improvement in both conduct and reporting. However, the quality of the handling of specific genetic issues remains disappointingly low. For a few key general quality issues, the authors compared their findings with findings in other fields of medicine and found that general quality was similar. On the basis of this review, the authors provide practical recommendations for the conduct and reporting of genetic meta-analyses.
Epidemiology and Infection - Current Issue
Volume 137 Issue 12
Tue, 01 Dec 2009 00:00:00 -0000
Epidemiology and Infection, Volume 137 Issue 12 Increased frequency in 2007 - now 8 issues per year! Epidemiology and Infection publishes original reports and reviews on all aspects of infection in humans and animals. Particular emphasis is given to the epidemiology, prevention and control of infectious diseases. The field covered is broad and includes the zoonoses, tropical infections, food hygiene, vaccine studies, statistics and the clinical, social and public-health aspects of infectious disease. Papers covering microbiology and immunology which have an epidemiological relevance are part of this broad field. Papers come from medical and veterinary scientists worldwide. It has become the key periodical in which to find the latest reports on recently discovered infections and new technology. For those concerned with policy and planning for the control of infections, the papers on mathematical modelling of epidemics caused by historical, current and emergent infections, will be of particular value. To celebrate 100 years of the journal, a series of important papers has been selected and each, together with a modern commentary on the paper by an expert, will be published on-line. This journal has now moved over to electronic submission, using the Scholar One system. Click here to go to the submission website. Guidance on how to upload your manuscript is available on the site by clicking "User Tutorials". Online manuscript submission (now) available, please go to http://mc.manuscriptcentral.com/cup/hyg
HYG volume 137 issue 12 Cover and Front matter
Miscellaneous Epidemiology and Infection, Volume 137 Issue 12 , pp f1-f2Abstract
Latest Issue of International Journal of Medical Microbiology
Editorial - ETOX turned twenty
Sebo P.
Pathogenomics of mobile genetic elements of toxigenic bacteria
Hacker J.Hochhut B.Middendorf B.Schneider G.Buchrieser C.Gottschalk G.Dobrindt U.
Sites:
American Type Culture Collection (ATCC): ATCC is a global bioresource center that stores and distributes biological materials such as cell lines, bacteria, animal and plant viruses and antisera, fungi, protozoa, algae, clones and other molecular genomic materials. We also manage databases and offer repository management and other labora...Antimicrobial Resistance Surveillance (BSAC Working Party): Information about antimicrobial resistance surveillance programmes run by BSAC (British Society for Antimicrobial Chemotherapy) and links to related sites.
Association for Professionals in Infection Control and Epidemiology, Inc.: Association for Professionals in Infection Control and Epidemiology is an association of healthcare professionals working to reduce, control and prevent infections associated with or acquired in a healthcare setting.
Bacterial Toxins: Friends or Foes?: Overview of the biochemistry and mechanism of action of bacterial toxins from the Center for Disease Control (CDC).
Candida albicans Pseudomonas Helicobacter epidemiology: Molecular epidemiology, virulence factors, virulence genes of pathogenic microorganisms.
CDC Division of Healthcare Quality Promotion: Issues in Healthcare Settings: Articles and statistics related to infectious diseases and hospitals and hospital personnel.
Clinical Microbiology Software: Interpretation and Report of Antimicrobial Susceptibility Test.: This is based on "rule-base expert system" and freeware. End-user can modify and add rules. This is assistant software to interpret and report antimicrobial( antibiotics ) susceptibility tests for clinical microbiology department,
Common Cold: A comprehensive source of information on the common cold that facilitates informed decisions about cold prevention and treatment.
Department of Medical Microbiology of the University of Zurich: Homepage of the Department of Medical Microbiology, University Zurich
Family Practice Notebook: Infectious Disease: Covers Bacteria, Emerging, Examination, Faver, Fever, Fungus, Helminth, Immune, Immunization, Parasite, Prion, Procedure, Sexually Transmitted Disease, Travel, Vector and Virus. Related chapters from other specialties include Dermatology, Ophthalmology, Gastroenterology, HIV, Laboratory, Neurolo...
General Practice Notebook - Infectious disease: Coverage of this medical speciality.
Genomics and Bacterial Pathogenesis: This review summarises the current methodologies used in genome analysis
Global Infectious Diseases and Epidemiology Network: GIDEON - Provides information, including disease, therapy and vaccine lists, support and demo of GIDEON. Medical software for the fields of infectious diseases and microbiology targeted at doctors and lab specialists.
Infection Control: Recent litterature abstracts on infection control updated every three months
Infectious disease information: Information about infectious disease in overview form, provided by Aventis.
Know Your Enemy: Determining the Genetic Blueprint of Disease-Causing Microorganisms, NIAID Fact Sheet: A fact sheet from the National Institute of Allergy and Infectious Diseases (NIAID) explaining, in simple terms, the objectives behind the finished and ongoing sequencing projects of pathogen genomes.
Medical Microbiology Synopsis: Site provides an overview of medical microbiology for students of medicine. Typical and atypical microbial flora are listed per specimen source and characterized in flowchart diagrams that can be easily memorized.
Microbiology at Mount Sinai Hospital, Toronto, Canada: We are a comprehensive, primary-source, Canadian microbiology and infectious diseases site. This site contains data from population and laboratory based surveillance programs, frequently requested papers and protocols, our current in use Lab Manual, as well as a forum for frequently asked q...
Physiopathological role of microbial metallogeny: Page personnelle de Stephane PLOUVIER
Reservoirs of Antibiotic Resistance Network: ROAR - Alliance for the Prudent Use of Antibiotics: A network, interactive database and information source organized around antibiotic resistance.
Reviews in Medical Microbiology: Journal of the Pathological Society of Great Britain and Ireland. Covering developments and techniques in medical microbiology, virology, mycology, parasitology, clinical microbiology, and hospital infection.
The United Kingdom National Culture collection: Fireworks Splice HTML
Using DNA Microarrays to Study Host-Microbe Interactions: This article provides a detailed introduction to DNA microarray technology and their application to the identification of host-pathogen interactions and virulence factors.
This directory is based on the Open Directory and may have been modified
